SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 2j7j TRANSCRIPTION FACTOR
IIIA
(Xenopus
laevis) 		5 / 12 HIS A  22
HIS A   5
LEU A  30
THR A  27
HIS A  26
 ZN  A1086 (-3.2A)
None
None
None
ZN  A1086 (-3.2A)
 1.47A 3lxeA-2j7jA:
undetectable		 3lxeA-2j7jA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 2j7j TRANSCRIPTION FACTOR
IIIA
(Xenopus
laevis) 		5 / 12 HIS A  22
HIS A   5
LEU A  30
THR A  27
HIS A  26
 ZN  A1086 (-3.2A)
None
None
None
ZN  A1086 (-3.2A)
 1.50A 3lxeB-2j7jA:
undetectable		 3lxeB-2j7jA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2j7j TRANSCRIPTION FACTOR
IIIA
(Xenopus
laevis) 		3 / 3 PHE A   6
CYH A   4
HIS A   5
 None
ZN  A1086 (-2.2A)
None
 1.17A 3u9fF-2j7jA:
undetectable		 3u9fF-2j7jA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2j7j TRANSCRIPTION FACTOR
IIIA
(Xenopus
laevis) 		3 / 3 PHE A   6
CYH A   4
HIS A   5
 None
ZN  A1086 (-2.2A)
None
 1.20A 3u9fG-2j7jA:
undetectable		 3u9fG-2j7jA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2j7j TRANSCRIPTION FACTOR
IIIA
(Xenopus
laevis) 		3 / 3 PHE A   6
CYH A   4
HIS A   5
 None
ZN  A1086 (-2.2A)
None
 1.28A 3u9fL-2j7jA:
undetectable		 3u9fL-2j7jA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2j7j TRANSCRIPTION FACTOR
IIIA
(Xenopus
laevis) 		3 / 3 PHE A   6
CYH A   4
HIS A   5
 None
ZN  A1086 (-2.2A)
None
 1.22A 3u9fS-2j7jA:
undetectable		 3u9fS-2j7jA:
19.00