SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 2j7m HYALURONIDASE
(Clostridium
perfringens) 		4 / 8 SER A 635
ALA A 645
ALA A 760
ARG A 690
 None
None
None
GAL  A1770 ( 2.8A)
 0.90A 2bxmA-2j7mA:
undetectable		 2bxmA-2j7mA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 2j7m HYALURONIDASE
(Clostridium
perfringens) 		4 / 7 VAL A 763
LEU A 674
TYR A 687
ILE A 698
 None
 1.00A 3avpA-2j7mA:
undetectable		 3avpA-2j7mA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 2j7m HYALURONIDASE
(Clostridium
perfringens) 		4 / 4 VAL A 765
ARG A 740
ILE A 698
THR A 628
 None
 1.19A 3cl9A-2j7mA:
undetectable		 3cl9A-2j7mA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2j7m HYALURONIDASE
(Clostridium
perfringens) 		4 / 7 ASP A 742
GLY A 700
THR A 699
ILE A 698
 None
 0.93A 4acaC-2j7mA:
undetectable		 4acaC-2j7mA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2j7m HYALURONIDASE
(Clostridium
perfringens) 		4 / 7 THR A 673
ARG A 740
ASP A 742
SER A 746
 None
 1.31A 5uxcA-2j7mA:
undetectable		 5uxcA-2j7mA:
18.94