SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 6 LEU A 802
ILE A 816
GLU A1020
ASP A1018
 None
 1.15A 1ditH-2j7nA:
undetectable
1ditP-2j7nA:
undetectable		 1ditH-2j7nA:
14.30
1ditP-2j7nA:
2.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 12 ALA A 480
GLY A 483
GLU A 419
ALA A 415
PRO A 472
 None
 1.15A 1mjqC-2j7nA:
undetectable
1mjqD-2j7nA:
undetectable		 1mjqC-2j7nA:
7.35
1mjqD-2j7nA:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 10 GLU A 419
ALA A 415
PRO A 472
ALA A 480
GLY A 483
 None
 1.13A 1mjqG-2j7nA:
undetectable
1mjqH-2j7nA:
undetectable		 1mjqG-2j7nA:
7.35
1mjqH-2j7nA:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 12 ALA A 480
GLY A 483
GLU A 419
ALA A 415
PRO A 472
 None
 1.15A 1mjqI-2j7nA:
undetectable
1mjqJ-2j7nA:
undetectable		 1mjqI-2j7nA:
7.35
1mjqJ-2j7nA:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		3 / 3 LEU A 651
PHE A 583
ARG A 528
 None
 0.90A 1xdkB-2j7nA:
undetectable		 1xdkB-2j7nA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 8 VAL A 929
PRO A 980
HIS A 983
ASP A 751
 None
 1.01A 2ddwA-2j7nA:
undetectable		 2ddwA-2j7nA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 8 ASP A1043
LEU A1050
SER A1072
LEU A 666
 None
 1.10A 2q0iA-2j7nA:
undetectable		 2q0iA-2j7nA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 12 ILE A 565
ALA A1076
ILE A 608
ILE A 607
THR A 544
 None
 1.10A 2rlcA-2j7nA:
undetectable		 2rlcA-2j7nA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 8 TYR A 762
ASN A 708
GLY A 712
GLU A 760
 None
 0.98A 2ys6A-2j7nA:
undetectable		 2ys6A-2j7nA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 12 ALA A 786
ALA A 918
VAL A1015
PHE A 991
LEU A 930
 None
 1.33A 3b0wB-2j7nA:
undetectable		 3b0wB-2j7nA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA303_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 4 ARG A 813
VAL A 810
LYS A 809
GLU A 803
 None
 1.14A 3deuA-2j7nA:
0.0		 3deuA-2j7nA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB304_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 4 ARG A 813
VAL A 810
LYS A 809
GLU A 803
 None
 1.17A 3deuB-2j7nA:
0.0		 3deuB-2j7nA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 10 LEU A 657
THR A1065
GLY A1057
MET A1051
PHE A1047
 None
 1.21A 3h9uA-2j7nA:
undetectable		 3h9uA-2j7nA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 10 LEU A 657
THR A1065
GLY A1057
MET A1051
PHE A1047
 None
 1.23A 3h9uC-2j7nA:
undetectable		 3h9uC-2j7nA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 10 LEU A 657
THR A1065
GLY A1057
MET A1051
PHE A1047
 None
 1.24A 3h9uD-2j7nA:
undetectable		 3h9uD-2j7nA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 8 ASP A 897
ASP A 893
ASP A 904
ASP A1176
 None
 1.09A 3havA-2j7nA:
undetectable		 3havA-2j7nA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		3 / 3 ASN A1080
ASP A 587
ARG A 962
 None
 0.89A 3k13A-2j7nA:
undetectable		 3k13A-2j7nA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 8 ASP A1011
ASP A1007
GLY A 710
ARG A 671
 MG  A3374 (-2.6A)
MG  A3374 (-2.6A)
None
None
 1.01A 3s3mA-2j7nA:
undetectable		 3s3mA-2j7nA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		3 / 3 LYS A 586
SER A 677
GLN A 673
 None
 1.22A 3si7A-2j7nA:
undetectable		 3si7A-2j7nA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		3 / 3 ASN A 501
ALA A 508
ARG A 397
 None
 0.86A 3tj7C-2j7nA:
undetectable
3tj7D-2j7nA:
undetectable		 3tj7C-2j7nA:
11.22
3tj7D-2j7nA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 10 ALA A 815
GLY A 817
LEU A 799
LEU A 820
ASN A 822
 None
 1.16A 3wdmB-2j7nA:
undetectable		 3wdmB-2j7nA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 9 ALA A 815
GLY A 817
LEU A 799
LEU A 820
ASN A 822
 None
 1.10A 3wdmC-2j7nA:
undetectable		 3wdmC-2j7nA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 12 PRO A 732
LEU A 728
LEU A 726
GLN A 736
ILE A 722
 None
 1.11A 4a7aB-2j7nA:
undetectable		 4a7aB-2j7nA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 11 ARG A 525
GLY A 737
VAL A 782
GLU A 781
VAL A 735
 None
 1.26A 4d9hA-2j7nA:
undetectable		 4d9hA-2j7nA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 11 ARG A 525
GLY A 737
VAL A 782
GLU A 781
VAL A 735
 None
 1.25A 4danA-2j7nA:
undetectable		 4danA-2j7nA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 11 HIS A 665
SER A1072
LEU A 526
ASP A 652
LEU A 657
 None
 1.32A 4foxC-2j7nA:
undetectable		 4foxC-2j7nA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 6 ASP A 771
ASP A 652
ASN A 660
ASP A 658
 None
 1.34A 4gkhJ-2j7nA:
undetectable		 4gkhJ-2j7nA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 11 GLY A 712
ALA A 924
GLY A 710
ILE A 971
LEU A 798
 None
 1.07A 4kt0A-2j7nA:
undetectable
4kt0J-2j7nA:
undetectable		 4kt0A-2j7nA:
21.15
4kt0J-2j7nA:
4.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		3 / 3 ASP A 452
VAL A 420
ASN A 474
 None
 0.78A 4lmnA-2j7nA:
undetectable		 4lmnA-2j7nA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 8 ILE A 912
ASN A 795
VAL A 801
LEU A 802
ILE A 971
 None
 1.23A 4r38D-2j7nA:
undetectable		 4r38D-2j7nA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 5 SER A1307
ARG A1230
GLY A1232
GLU A1233
 None
 1.14A 5btiA-2j7nA:
undetectable
5btiB-2j7nA:
undetectable		 5btiA-2j7nA:
19.42
5btiB-2j7nA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 5 SER A1307
ARG A1230
GLY A1232
GLU A1233
 None
 1.16A 5btiC-2j7nA:
undetectable
5btiD-2j7nA:
undetectable		 5btiC-2j7nA:
19.42
5btiD-2j7nA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 5 TYR A 890
PHE A 841
LEU A 898
PRO A 885
 None
 1.39A 5csyB-2j7nA:
undetectable		 5csyB-2j7nA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 6 LYS A1119
ASP A1007
GLY A 710
ASP A 709
 None
MG  A3374 (-2.6A)
None
None
 1.44A 5hp1C-2j7nA:
undetectable		 5hp1C-2j7nA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 6 LYS A1119
ASP A1009
GLY A 710
ASP A1007
 None
MG  A3374 (-2.4A)
None
MG  A3374 (-2.6A)
 1.41A 5hp1C-2j7nA:
undetectable		 5hp1C-2j7nA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		3 / 3 VAL A 977
SER A 992
MET A 922
 None
 0.87A 5ikqA-2j7nA:
undetectable		 5ikqA-2j7nA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		3 / 3 LEU A 798
TYR A 919
SER A 917
 None
 0.87A 5iktA-2j7nA:
undetectable		 5iktA-2j7nA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 5 GLY A1112
SER A1004
ARG A 962
GLY A1005
 None
 1.07A 5kprA-2j7nA:
undetectable		 5kprA-2j7nA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 8 ILE A1231
ARG A1305
ALA A1309
PHE A1320
 None
 0.93A 5m0oC-2j7nA:
undetectable		 5m0oC-2j7nA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		4 / 6 GLU A 872
ARG A 901
ASP A 897
ASP A 869
 None
 1.01A 5zw4A-2j7nA:
undetectable		 5zw4A-2j7nA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 12 SER A 963
SER A 917
LEU A 796
PHE A 943
TYR A 919
 None
 1.40A 6a93A-2j7nA:
2.7		 6a93A-2j7nA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 12 LEU A 898
SER A 908
CYH A 903
ILE A1175
ASP A1176
 None
 1.19A 6bxnA-2j7nA:
undetectable		 6bxnA-2j7nA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 12 LEU A 898
SER A 908
CYH A 903
ILE A1175
ASP A1176
 None
 1.15A 6bxnB-2j7nA:
undetectable		 6bxnB-2j7nA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 2j7n RNA-DEPENDENT RNA
POLYMERASE
(Neurospora
crassa) 		5 / 10 VAL A 493
LEU A 494
SER A 495
LEU A 539
GLY A 523
 None
 1.09A 6eu9B-2j7nA:
undetectable		 6eu9B-2j7nA:
5.52