SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		7 / 12 ALA A  60
SER A  61
LYS A  64
SER A 122
ASN A 124
LYS A 219
GLY A 221
 None
 0.26A 1ghmA-2j7vA:
30.5		 1ghmA-2j7vA:
27.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		8 / 12 ALA A  60
SER A  61
LYS A  64
SER A 122
ASN A 124
THR A 202
LYS A 219
GLY A 221
 None
 0.77A 1i2wA-2j7vA:
32.5		 1i2wA-2j7vA:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 ALA A  60
SER A  61
LYS A  64
ASN A 124
THR A 202
GLY A 221
 None
 0.81A 1i2wB-2j7vA:
32.5		 1i2wB-2j7vA:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 ALA A  60
SER A  61
LYS A  64
SER A 122
ASN A 124
GLY A 221
 None
 0.34A 1i2wB-2j7vA:
32.5		 1i2wB-2j7vA:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 ALA A  36
ARG A 249
GLY A 256
ILE A 260
LEU A 172
 None
 1.21A 1kglA-2j7vA:
undetectable		 1kglA-2j7vA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 8 ALA A 244
GLY A  52
GLY A  37
PRO A  58
ALA A  59
 None
 1.24A 1sguA-2j7vA:
undetectable		 1sguA-2j7vA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		7 / 12 SER A  61
LYS A  64
SER A 122
ASN A 124
THR A 202
LYS A 219
GLY A 221
 None
 0.70A 1ymxA-2j7vA:
33.6		 1ymxA-2j7vA:
27.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 SER A  61
LYS A  64
SER A 122
ASN A 124
LYS A 219
GLY A 221
 None
 0.27A 1ymxB-2j7vA:
33.6		 1ymxB-2j7vA:
27.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		4 / 7 GLY A 211
ASP A 234
TYR A 268
ARG A 240
 None
 1.22A 3arrA-2j7vA:
undetectable		 3arrA-2j7vA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LYS A  64
SER A 122
ASN A 124
LYS A 219
GLY A 221
 None
 0.33A 3hlwA-2j7vA:
33.6		 3hlwA-2j7vA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 SER A 122
ASN A 124
THR A 202
LYS A 219
THR A 220
GLY A 221
 None
 0.82A 3hlwB-2j7vA:
33.7		 3hlwB-2j7vA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LYS A  64
ASN A 124
LYS A 219
THR A 220
GLY A 221
 None
 0.29A 3huoA-2j7vA:
33.7		 3huoA-2j7vA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LEU A  11
GLY A 182
GLY A 180
LEU A 193
TRP A 147
 None
 1.08A 3i5uA-2j7vA:
undetectable		 3i5uA-2j7vA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LEU A  11
GLY A 182
GLY A 180
LEU A 193
TRP A 147
 None
 1.11A 3i5uB-2j7vA:
undetectable		 3i5uB-2j7vA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 ALA A  60
SER A  61
LYS A  64
ASN A 124
THR A 220
GLY A 221
 None
 0.42A 3mzeA-2j7vA:
21.9		 3mzeA-2j7vA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LYS A  64
SER A 122
ASN A 124
LYS A 219
GLY A 221
 None
 0.35A 3q07A-2j7vA:
33.6		 3q07A-2j7vA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LYS A  64
SER A 122
ASN A 124
LYS A 219
GLY A 221
 None
 0.42A 3q07B-2j7vA:
33.5		 3q07B-2j7vA:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		7 / 12 ALA A  60
SER A  61
SER A 122
ASN A 124
LYS A 219
THR A 220
GLY A 221
 None
 0.42A 3sh8A-2j7vA:
31.9		 3sh8A-2j7vA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		7 / 12 ALA A  60
SER A  61
LYS A  64
SER A 122
ASN A 124
LYS A 219
GLY A 221
 None
 0.39A 3sh8B-2j7vA:
31.4		 3sh8B-2j7vA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		7 / 12 LYS A  64
SER A 122
ASN A 124
THR A 202
LYS A 219
THR A 220
GLY A 221
 None
 0.83A 4euzA-2j7vA:
32.4		 4euzA-2j7vA:
26.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 10 SER A 122
ASN A 124
LYS A 219
THR A 220
GLY A 221
ALA A  60
 None
 1.37A 4fh2A-2j7vA:
29.2		 4fh2A-2j7vA:
27.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		7 / 12 ALA A  60
SER A  61
SER A 122
ASN A 124
LYS A 219
THR A 220
GLY A 221
 None
 0.40A 4n9kA-2j7vA:
32.3		 4n9kA-2j7vA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		7 / 12 ALA A  60
SER A  61
SER A 122
ASN A 124
LYS A 219
THR A 220
GLY A 221
 None
 0.43A 4n9kB-2j7vA:
32.3		 4n9kB-2j7vA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LEU A 177
GLY A 180
LEU A 194
MET A 232
VAL A 233
 None
 1.40A 4ojbA-2j7vA:
undetectable		 4ojbA-2j7vA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LEU A 177
GLY A 180
LEU A 194
MET A 232
VAL A 233
 None
 1.39A 4okbA-2j7vA:
undetectable		 4okbA-2j7vA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LEU A 177
GLY A 180
LEU A 194
MET A 232
VAL A 233
 None
 1.39A 4okxA-2j7vA:
undetectable		 4okxA-2j7vA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 LEU A 177
GLY A 180
LEU A 194
MET A 232
VAL A 233
 None
 1.36A 4olmA-2j7vA:
undetectable		 4olmA-2j7vA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 SER A 122
ASN A 124
LYS A 219
THR A 220
GLY A 221
ALA A  60
 None
 1.46A 4pm9A-2j7vA:
33.3		 4pm9A-2j7vA:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 ALA A  60
SER A  61
SER A 122
ASN A 124
LYS A 219
GLY A 221
 None
 0.38A 5ghyA-2j7vA:
32.2		 5ghyA-2j7vA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 ALA A  60
SER A  61
SER A 122
ASN A 124
LYS A 219
GLY A 221
 None
 0.37A 5ghyB-2j7vA:
32.2		 5ghyB-2j7vA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		7 / 11 ALA A  60
SER A  61
SER A 122
ASN A 124
LYS A 219
THR A 220
GLY A 221
 None
 0.42A 5ghzA-2j7vA:
32.5		 5ghzA-2j7vA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		7 / 10 ALA A  60
SER A  61
SER A 122
ASN A 124
LYS A 219
THR A 220
GLY A 221
 None
 0.41A 5ghzB-2j7vA:
32.3		 5ghzB-2j7vA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 11 SER A  61
GLY A 228
VAL A 227
ASP A 229
ILE A 260
 None
 1.23A 5i3cC-2j7vA:
undetectable		 5i3cC-2j7vA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		4 / 5 TYR A 109
ARG A  85
MET A  88
THR A  87
 None
 1.25A 5z86J-2j7vA:
undetectable		 5z86J-2j7vA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 SER A  61
SER A 122
THR A 202
LYS A 219
THR A 220
GLY A 221
 None
 0.81A 6b69A-2j7vA:
32.0
6b69B-2j7vA:
32.1		 6b69A-2j7vA:
12.71
6b69B-2j7vA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		6 / 12 SER A  61
SER A 122
THR A 202
LYS A 219
THR A 220
GLY A 221
 None
 0.78A 6b69D-2j7vA:
32.0		 6b69D-2j7vA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 SER A  61
SER A 122
LYS A 219
THR A 220
GLY A 221
 None
 0.34A 6b6aD-2j7vA:
32.1		 6b6aD-2j7vA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 SER A  61
SER A 122
LYS A 219
THR A 220
GLY A 221
 None
 0.36A 6b6cA-2j7vA:
32.2		 6b6cA-2j7vA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		5 / 12 SER A  61
SER A 122
LYS A 219
THR A 220
GLY A 221
 None
 0.43A 6b6fA-2j7vA:
32.0		 6b6fA-2j7vA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2j7v TLL2115 PROTEIN
(Synechococcus
elongatus) 		4 / 6 SER A 264
GLN A 269
GLU A 258
THR A 204
 None
 1.49A 6djzA-2j7vA:
undetectable		 6djzA-2j7vA:
20.00