SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 2j87 THYMIDINE KINASE
(Vaccinia
virus) 		5 / 9 GLY A  84
ASP A  82
ILE A 105
ILE A  10
ILE A   6
 None
TTP  A 300 (-3.0A)
None
None
None
 0.90A 3s53A-2j87A:
undetectable		 3s53A-2j87A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 2j87 THYMIDINE KINASE
(Vaccinia
virus) 		5 / 12 GLY A 162
ASN A 163
MET A 165
ILE A 160
LEU A 109
 None
None
None
TTP  A 300 (-4.2A)
TTP  A 300 (-4.8A)
 1.36A 4kovA-2j87A:
undetectable		 4kovA-2j87A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOY_A_CSCA214_1
(UNCHARACTERIZED
PROTEIN)		 2j87 THYMIDINE KINASE
(Vaccinia
virus) 		5 / 11 GLY A 162
ASN A 163
MET A 165
ILE A 160
LEU A 109
 None
None
None
TTP  A 300 (-4.2A)
TTP  A 300 (-4.8A)
 1.40A 4koyA-2j87A:
undetectable		 4koyA-2j87A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2j87 THYMIDINE KINASE
(Vaccinia
virus) 		4 / 5 TYR A 166
GLY A 111
ASP A 110
GLU A  83
 TTP  A 300 (-4.0A)
None
None
TTP  A 300 (-3.9A)
 1.01A 4nkvD-2j87A:
undetectable		 4nkvD-2j87A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 2j87 THYMIDINE KINASE
(Vaccinia
virus) 		3 / 3 LYS A 102
ILE A  79
ILE A  38
 None
 0.71A 4y0qA-2j87A:
undetectable		 4y0qA-2j87A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 2j87 THYMIDINE KINASE
(Vaccinia
virus) 		4 / 8 ARG A 115
GLY A  11
PRO A  12
ASP A 110
 None
 1.05A 5kf8A-2j87A:
undetectable		 5kf8A-2j87A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 2j87 THYMIDINE KINASE
(Vaccinia
virus) 		4 / 8 ARG A 115
GLY A  11
PRO A  12
ASP A 110
 None
 1.01A 5kgpA-2j87A:
undetectable		 5kgpA-2j87A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 2j87 THYMIDINE KINASE
(Vaccinia
virus) 		4 / 8 ARG A 115
GLY A  11
PRO A  12
ASP A 110
 None
 1.00A 5kgpB-2j87A:
undetectable		 5kgpB-2j87A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 2j87 THYMIDINE KINASE
(Vaccinia
virus) 		4 / 8 LEU A  66
ALA A 108
VAL A  69
TYR A  40
 None
 0.95A 5nu7A-2j87A:
undetectable		 5nu7A-2j87A:
19.29