SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 2j89 METHIONINE SULFOXIDE
REDUCTASE A
(Populus
trichocarpa) 		4 / 6 PHE A  39
ASP A  29
ASP A  30
PRO A  33
 None
 1.39A 1ilqA-2j89A:
undetectable
1ilqC-2j89A:
undetectable		 1ilqA-2j89A:
15.20
1ilqC-2j89A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2j89 METHIONINE SULFOXIDE
REDUCTASE A
(Populus
trichocarpa) 		4 / 8 LEU A 180
TYR A 179
TRP A  48
GLY A 204
 None
None
BME  A 207 ( 4.2A)
None
 0.76A 5f1aA-2j89A:
undetectable		 5f1aA-2j89A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2j89 METHIONINE SULFOXIDE
REDUCTASE A
(Populus
trichocarpa) 		4 / 7 LEU A 180
TYR A 179
TRP A  48
GLY A 204
 None
None
BME  A 207 ( 4.2A)
None
 0.72A 5f1aB-2j89A:
undetectable		 5f1aB-2j89A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB203_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 2j89 METHIONINE SULFOXIDE
REDUCTASE A
(Populus
trichocarpa) 		5 / 9 ASN A  88
TYR A 134
GLY A 132
VAL A  90
HIS A 113
 None
 1.11A 5f8yB-2j89A:
undetectable		 5f8yB-2j89A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2j89 METHIONINE SULFOXIDE
REDUCTASE A
(Populus
trichocarpa) 		4 / 8 THR A 137
TYR A 135
ARG A  92
GLN A  41
 None
 1.24A 5tzoA-2j89A:
undetectable		 5tzoA-2j89A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2j89 METHIONINE SULFOXIDE
REDUCTASE A
(Populus
trichocarpa) 		4 / 8 THR A 137
TYR A 135
ARG A  92
GLN A  41
 None
 1.20A 5tzoB-2j89A:
undetectable		 5tzoB-2j89A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2j89 METHIONINE SULFOXIDE
REDUCTASE A
(Populus
trichocarpa) 		4 / 8 THR A 137
TYR A 135
ARG A  92
GLN A  41
 None
 1.26A 5tzoC-2j89A:
undetectable		 5tzoC-2j89A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 2j89 METHIONINE SULFOXIDE
REDUCTASE A
(Populus
trichocarpa) 		5 / 12 ILE A 159
SER A 131
LEU A 154
ASP A 107
ILE A 133
 None
 1.39A 6dwnB-2j89A:
undetectable		 6dwnB-2j89A:
16.67