SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j8k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A  97
ILE A  91
GLY A  89
ALA A  90
LEU A  87
None
1.06A 1cqeA-2j8kA:
undetectable
1cqeA-2j8kA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A  97
ILE A  91
GLY A  89
ALA A  90
LEU A  87
None
1.05A 1cqeB-2j8kA:
undetectable
1cqeB-2j8kA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)
2j8k NP275-NP276
(Nostoc
punctiforme)
4 / 5 ALA A 140
ALA A 115
ALA A  95
GLN A  99
None
None
None
MES  A1176 (-3.3A)
0.87A 2nyrB-2j8kA:
undetectable
2nyrB-2j8kA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 GLY A  59
GLY A  39
ILE A  81
ASN A 101
ALA A 100
None
0.92A 2vdvE-2j8kA:
undetectable
2vdvE-2j8kA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 11 GLY A  59
GLY A  39
ILE A  81
ASN A 101
ALA A 100
None
0.92A 2vdvF-2j8kA:
undetectable
2vdvF-2j8kA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A 157
THR A 158
ASP A 136
ALA A 155
ILE A 171
None
1.15A 3a3bA-2j8kA:
undetectable
3a3bA-2j8kA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A 112
LEU A  77
GLY A  89
ALA A  90
LEU A  67
None
1.21A 3pghA-2j8kA:
undetectable
3pghA-2j8kA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 10 ALA A 105
LEU A 112
LEU A 122
ASP A 121
ILE A 117
None
1.09A 3wdmB-2j8kA:
undetectable
3wdmB-2j8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 10 ALA A 125
LEU A 112
LEU A 122
ASP A 121
ILE A 117
None
1.12A 3wdmB-2j8kA:
undetectable
3wdmB-2j8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 10 ALA A 140
LEU A 127
LEU A 137
LEU A  97
ASN A  98
None
None
None
None
MES  A1176 (-2.7A)
1.05A 3wdmB-2j8kA:
undetectable
3wdmB-2j8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 9 ALA A 105
LEU A 112
LEU A 122
ASP A 121
ILE A 117
None
1.11A 3wdmC-2j8kA:
undetectable
3wdmC-2j8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 10 ALA A 105
LEU A  92
LEU A 102
LEU A  62
ASN A  63
None
1.16A 3wdmD-2j8kA:
undetectable
3wdmD-2j8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 10 ALA A 105
LEU A 112
LEU A 122
ASP A 121
ILE A 117
None
1.04A 3wdmD-2j8kA:
undetectable
3wdmD-2j8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 10 ALA A 125
LEU A 112
LEU A 122
ASP A 121
ILE A 117
None
1.00A 3wdmD-2j8kA:
undetectable
3wdmD-2j8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 10 ALA A 140
LEU A 127
LEU A 137
LEU A  97
ASN A  98
None
None
None
None
MES  A1176 (-2.7A)
0.97A 3wdmD-2j8kA:
undetectable
3wdmD-2j8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 10 ALA A 145
LEU A 132
ASP A 121
LEU A 102
ILE A 117
None
1.10A 3wdmD-2j8kA:
undetectable
3wdmD-2j8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
4 / 8 ALA A 110
ASN A 106
LEU A 102
ALA A  65
None
0.72A 4wboB-2j8kA:
undetectable
4wboB-2j8kA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
4 / 8 ALA A 120
ASN A 116
LEU A 112
ALA A  75
None
MES  A1176 (-3.2A)
None
None
0.67A 4wboB-2j8kA:
undetectable
4wboB-2j8kA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
4 / 8 ALA A 130
ASN A 126
LEU A 122
ALA A  85
None
0.62A 4wboB-2j8kA:
undetectable
4wboB-2j8kA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
4 / 8 ALA A 150
ASN A 146
LEU A 142
ALA A 105
None
0.66A 4wboB-2j8kA:
undetectable
4wboB-2j8kA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)
2j8k NP275-NP276
(Nostoc
punctiforme)
4 / 8 ALA A 165
ASN A 161
LEU A 157
ALA A 120
None
0.66A 4wboB-2j8kA:
undetectable
4wboB-2j8kA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 8 LEU A  37
LEU A  47
ALA A  70
LEU A  57
ALA A  55
None
1.08A 4z90A-2j8kA:
undetectable
4z90B-2j8kA:
undetectable
4z90C-2j8kA:
undetectable
4z90D-2j8kA:
undetectable
4z90E-2j8kA:
undetectable
4z90A-2j8kA:
18.60
4z90B-2j8kA:
18.60
4z90C-2j8kA:
18.60
4z90D-2j8kA:
18.60
4z90E-2j8kA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 8 LEU A  57
LEU A  67
ALA A  90
LEU A  77
ALA A  75
None
1.05A 4z90A-2j8kA:
undetectable
4z90B-2j8kA:
undetectable
4z90C-2j8kA:
undetectable
4z90D-2j8kA:
undetectable
4z90E-2j8kA:
undetectable
4z90A-2j8kA:
18.60
4z90B-2j8kA:
18.60
4z90C-2j8kA:
18.60
4z90D-2j8kA:
18.60
4z90E-2j8kA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 8 LEU A  92
LEU A 102
ALA A 125
LEU A 112
ALA A 110
None
1.10A 4z90A-2j8kA:
undetectable
4z90B-2j8kA:
undetectable
4z90C-2j8kA:
undetectable
4z90D-2j8kA:
undetectable
4z90E-2j8kA:
undetectable
4z90A-2j8kA:
18.60
4z90B-2j8kA:
18.60
4z90C-2j8kA:
18.60
4z90D-2j8kA:
18.60
4z90E-2j8kA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 8 LEU A 102
LEU A 112
ALA A 135
LEU A 122
ALA A 120
None
1.10A 4z90A-2j8kA:
undetectable
4z90B-2j8kA:
undetectable
4z90C-2j8kA:
undetectable
4z90D-2j8kA:
undetectable
4z90E-2j8kA:
undetectable
4z90A-2j8kA:
18.60
4z90B-2j8kA:
18.60
4z90C-2j8kA:
18.60
4z90D-2j8kA:
18.60
4z90E-2j8kA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 8 LEU A 122
LEU A 132
ALA A 155
LEU A 142
ALA A 140
None
1.10A 4z90A-2j8kA:
undetectable
4z90B-2j8kA:
undetectable
4z90C-2j8kA:
undetectable
4z90D-2j8kA:
undetectable
4z90E-2j8kA:
undetectable
4z90A-2j8kA:
18.60
4z90B-2j8kA:
18.60
4z90C-2j8kA:
18.60
4z90D-2j8kA:
18.60
4z90E-2j8kA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 8 LEU A 127
LEU A 137
ALA A 160
LEU A 147
ALA A 145
None
1.03A 4z90A-2j8kA:
undetectable
4z90B-2j8kA:
undetectable
4z90C-2j8kA:
undetectable
4z90D-2j8kA:
undetectable
4z90E-2j8kA:
undetectable
4z90A-2j8kA:
18.60
4z90B-2j8kA:
18.60
4z90C-2j8kA:
18.60
4z90D-2j8kA:
18.60
4z90E-2j8kA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2j8k NP275-NP276
(Nostoc
punctiforme)
6 / 9 LEU A  22
LEU A   6
LEU A  32
ALA A  35
LEU A  42
ALA A  40
None
1.24A 4z91F-2j8kA:
undetectable
4z91G-2j8kA:
undetectable
4z91H-2j8kA:
undetectable
4z91I-2j8kA:
undetectable
4z91J-2j8kA:
undetectable
4z91F-2j8kA:
18.60
4z91G-2j8kA:
18.60
4z91H-2j8kA:
18.60
4z91I-2j8kA:
18.60
4z91J-2j8kA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
2j8k NP275-NP276
(Nostoc
punctiforme)
6 / 9 LEU A 107
ALA A 105
LEU A  87
ALA A  85
LEU A  77
ALA A 100
None
1.17A 4z91F-2j8kA:
undetectable
4z91G-2j8kA:
undetectable
4z91H-2j8kA:
undetectable
4z91I-2j8kA:
undetectable
4z91J-2j8kA:
undetectable
4z91F-2j8kA:
18.60
4z91G-2j8kA:
18.60
4z91H-2j8kA:
18.60
4z91I-2j8kA:
18.60
4z91J-2j8kA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)
2j8k NP275-NP276
(Nostoc
punctiforme)
6 / 12 LEU A  82
LEU A  22
MET A   1
ILE A  30
ALA A  55
LEU A  32
None
1.32A 5ienA-2j8kA:
undetectable
5ienA-2j8kA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A  82
MET A   1
ILE A  30
ALA A  55
LEU A  32
None
0.89A 5ienB-2j8kA:
undetectable
5ienB-2j8kA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)
2j8k NP275-NP276
(Nostoc
punctiforme)
6 / 12 LEU A  87
MET A   1
LEU A  67
ILE A  30
ALA A  55
LEU A  32
None
1.49A 5ienB-2j8kA:
undetectable
5ienB-2j8kA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A  92
LEU A 132
ALA A 130
LEU A 107
ILE A 117
None
0.98A 5itzB-2j8kA:
undetectable
5itzB-2j8kA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A 112
LEU A 152
ALA A 150
LEU A 127
ASN A 146
None
1.10A 5itzB-2j8kA:
undetectable
5itzB-2j8kA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A 112
LEU A  77
GLY A  89
ALA A  90
LEU A  67
None
1.07A 5jvzA-2j8kA:
undetectable
5jvzA-2j8kA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A 112
LEU A  77
GLY A  89
ALA A  90
LEU A  67
None
1.07A 5jvzB-2j8kA:
undetectable
5jvzB-2j8kA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 9 THR A  61
ALA A  60
ALA A  40
GLY A  64
ALA A  45
None
1.09A 5l5zK-2j8kA:
undetectable
5l5zL-2j8kA:
undetectable
5l5zK-2j8kA:
21.16
5l5zL-2j8kA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 9 THR A  61
ALA A  60
ALA A  40
GLY A  64
ALA A  45
None
1.09A 5l5zY-2j8kA:
undetectable
5l5zZ-2j8kA:
undetectable
5l5zY-2j8kA:
21.16
5l5zZ-2j8kA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
2j8k NP275-NP276
(Nostoc
punctiforme)
4 / 6 ILE A  91
ILE A  30
LEU A  47
PHE A  17
None
1.00A 5vkqB-2j8kA:
undetectable
5vkqC-2j8kA:
undetectable
5vkqB-2j8kA:
8.21
5vkqC-2j8kA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
2j8k NP275-NP276
(Nostoc
punctiforme)
4 / 6 ILE A  91
ILE A  30
LEU A  47
PHE A  17
None
1.01A 5vkqC-2j8kA:
undetectable
5vkqD-2j8kA:
undetectable
5vkqC-2j8kA:
8.21
5vkqD-2j8kA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)
2j8k NP275-NP276
(Nostoc
punctiforme)
5 / 12 LEU A  47
ALA A  45
LEU A  22
ILE A  30
ALA A  50
None
1.02A 5xiwB-2j8kA:
undetectable
5xiwB-2j8kA:
20.00