SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j8w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 2j8w CYTOCHROME C'
(Rubrivivax
gelatinosus) 		4 / 5 ALA A  20
GLY A 116
CYH A 119
HIS A 123
 HEM  A1129 ( 3.7A)
None
HEM  A1129 (-1.8A)
HEM  A1129 (-3.4A)
 0.16A 2yldA-2j8wA:
21.2		 2yldA-2j8wA:
47.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 2j8w CYTOCHROME C'
(Rubrivivax
gelatinosus) 		4 / 5 ALA A  20
GLY A 116
CYH A 119
HIS A 123
 HEM  A1129 ( 3.7A)
None
HEM  A1129 (-1.8A)
HEM  A1129 (-3.4A)
 0.21A 2ylgA-2j8wA:
21.3		 2ylgA-2j8wA:
47.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 2j8w CYTOCHROME C'
(Rubrivivax
gelatinosus) 		4 / 5 ALA A  20
GLY A 116
CYH A 119
HIS A 123
 HEM  A1129 ( 3.7A)
None
HEM  A1129 (-1.8A)
HEM  A1129 (-3.4A)
 0.16A 3zwiA-2j8wA:
21.2		 3zwiA-2j8wA:
47.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 2j8w CYTOCHROME C'
(Rubrivivax
gelatinosus) 		4 / 4 ALA A  20
GLY A 116
CYH A 119
HIS A 123
 HEM  A1129 ( 3.7A)
None
HEM  A1129 (-1.8A)
HEM  A1129 (-3.4A)
 0.17A 4cipA-2j8wA:
21.3		 4cipA-2j8wA:
47.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2j8w CYTOCHROME C'
(Rubrivivax
gelatinosus) 		5 / 12 ILE A  19
ALA A  15
GLY A 116
PHE A  89
VAL A  93
 HEM  A1129 (-4.9A)
None
None
HEM  A1129 (-3.9A)
None
 1.21A 5i75A-2j8wA:
undetectable		 5i75A-2j8wA:
13.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 2j8w CYTOCHROME C'
(Rubrivivax
gelatinosus) 		4 / 5 ALA A  20
GLY A 116
CYH A 119
HIS A 123
 HEM  A1129 ( 3.7A)
None
HEM  A1129 (-1.8A)
HEM  A1129 (-3.4A)
 0.23A 5jliA-2j8wA:
21.4		 5jliA-2j8wA:
47.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 2j8w CYTOCHROME C'
(Rubrivivax
gelatinosus) 		4 / 4 ALA A  20
GLY A 116
CYH A 119
HIS A 123
 HEM  A1129 ( 3.7A)
None
HEM  A1129 (-1.8A)
HEM  A1129 (-3.4A)
 0.20A 5jslA-2j8wA:
21.3		 5jslA-2j8wA:
48.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 2j8w CYTOCHROME C'
(Rubrivivax
gelatinosus) 		4 / 5 ALA A  20
GLY A 116
CYH A 119
HIS A 123
 HEM  A1129 ( 3.7A)
None
HEM  A1129 (-1.8A)
HEM  A1129 (-3.4A)
 0.19A 5jt4A-2j8wA:
21.5		 5jt4A-2j8wA:
47.29