SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j92'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		4 / 7 PHE A  72
THR A 180
VAL A  36
GLY A  35
 None
 0.97A 2a1mA-2j92A:
undetectable		 2a1mA-2j92A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		4 / 7 LEU A 199
ALA A  40
GLY A  35
PHE A 103
 None
 0.90A 2wq5A-2j92A:
undetectable		 2wq5A-2j92A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		5 / 12 HIS A  46
ASP A  84
GLY A 161
ALA A 163
ALA A 183
 None
 0.61A 3sudA-2j92A:
10.2		 3sudA-2j92A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		5 / 12 HIS A  46
ASP A  84
GLY A 161
ALA A 163
ALA A 183
 None
 0.64A 3sudB-2j92A:
10.3		 3sudB-2j92A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		5 / 12 HIS A  46
ASP A  84
GLY A 161
ALA A 163
ALA A 183
 None
 0.77A 3sudC-2j92A:
9.8		 3sudC-2j92A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		5 / 12 HIS A  46
ASP A  84
GLY A 161
ALA A 163
ALA A 183
 None
 0.66A 3sudD-2j92A:
10.6		 3sudD-2j92A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		5 / 12 GLY A 189
GLY A 187
SER A 182
GLU A 132
ALA A 153
 None
 1.35A 3t7sD-2j92A:
undetectable		 3t7sD-2j92A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		4 / 6 THR A  16
GLY A  35
ILE A  99
LEU A  42
 None
 1.24A 4acaC-2j92A:
2.5		 4acaC-2j92A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		4 / 6 GLY A 161
TYR A 162
GLY A 164
ASN A 121
 None
 0.92A 5k4pA-2j92A:
undetectable		 5k4pA-2j92A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		5 / 12 GLY A 179
VAL A  12
VAL A 115
ALA A 169
LEU A 168
 None
 0.85A 5kocA-2j92A:
undetectable		 5kocA-2j92A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2j92 PICORNAIN 3C
(Foot-and-mouth
disease
virus) 		5 / 12 GLY A 179
VAL A  12
VAL A 115
ALA A 169
LEU A 168
 None
 0.87A 5kpcA-2j92A:
undetectable		 5kpcA-2j92A:
19.85