SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jam'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FMO_E_ADNE351_1
(CAMP-DEPENDENT
PROTEIN KINASE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		7 / 12 LEU A  29
GLY A  30
VAL A  37
ALA A  50
VAL A  82
VAL A 101
ASN A 149
 J60  A1305 (-3.9A)
None
J60  A1305 (-4.8A)
J60  A1305 (-3.3A)
J60  A1305 ( 4.7A)
J60  A1305 (-3.9A)
None
 0.76A 1fmoE-2jamA:
19.7		 1fmoE-2jamA:
30.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 10 ILE A 278
ALA A 283
PHE A 254
ILE A 125
THR A 282
 None
 1.28A 1j3jA-2jamA:
undetectable		 1j3jA-2jamA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_A_BEZA1501_0
(RAS-RELATED PROTEIN
RAB-9A)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 5 ILE A 255
TRP A 244
LEU A 259
PRO A 219
 None
 1.31A 1s8fA-2jamA:
undetectable
1s8fB-2jamA:
undetectable		 1s8fA-2jamA:
20.50
1s8fB-2jamA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 9 LEU A  29
VAL A  37
LEU A  84
LEU A  96
LEU A 100
 J60  A1305 (-3.9A)
J60  A1305 (-4.8A)
None
None
J60  A1305 (-4.4A)
 0.42A 1xkkA-2jamA:
14.8		 1xkkA-2jamA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 9 VAL A  37
LYS A  52
LEU A  84
LEU A  96
LEU A 100
 J60  A1305 (-4.8A)
EDO  A1304 ( 2.9A)
None
None
J60  A1305 (-4.4A)
 0.59A 1xkkA-2jamA:
14.8		 1xkkA-2jamA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 283
PHE A 254
ILE A 125
THR A 282
 None
 1.21A 2blaA-2jamA:
undetectable		 2blaA-2jamA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		7 / 12 LEU A  29
GLY A  30
VAL A  37
ALA A  50
VAL A 101
ASN A 149
ASP A 165
 J60  A1305 (-3.9A)
None
J60  A1305 (-4.8A)
J60  A1305 (-3.3A)
J60  A1305 (-3.9A)
None
J60  A1305 ( 3.6A)
 0.94A 2fumA-2jamA:
21.2		 2fumA-2jamA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		7 / 12 LEU A  29
GLY A  30
VAL A  37
ALA A  50
VAL A 101
ASN A 149
ASP A 165
 J60  A1305 (-3.9A)
None
J60  A1305 (-4.8A)
J60  A1305 (-3.3A)
J60  A1305 (-3.9A)
None
J60  A1305 ( 3.6A)
 0.90A 2fumB-2jamA:
20.9		 2fumB-2jamA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_C_MIXC2539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		6 / 12 LEU A  29
GLY A  30
VAL A  37
ALA A  50
VAL A 101
ASN A 149
 J60  A1305 (-3.9A)
None
J60  A1305 (-4.8A)
J60  A1305 (-3.3A)
J60  A1305 (-3.9A)
None
 0.78A 2fumC-2jamA:
21.4		 2fumC-2jamA:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_D_NILD600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 6 LEU A  29
VAL A  37
LYS A  52
LEU A 151
 J60  A1305 (-3.9A)
J60  A1305 (-4.8A)
EDO  A1304 ( 2.9A)
None
 0.68A 3cs9D-2jamA:
17.8		 3cs9D-2jamA:
28.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 4 ILE A 278
PHE A 254
ILE A 125
THR A 282
 None
 1.06A 3ia4A-2jamA:
undetectable		 3ia4A-2jamA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXK_A_MI1A1125_1
(TYROSINE-PROTEIN
KINASE JAK3)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		7 / 12 LEU A  29
GLY A  30
VAL A  37
ALA A  50
LYS A  52
VAL A  82
ASP A 165
 J60  A1305 (-3.9A)
None
J60  A1305 (-4.8A)
J60  A1305 (-3.3A)
EDO  A1304 ( 2.9A)
J60  A1305 ( 4.7A)
J60  A1305 ( 3.6A)
 0.75A 3lxkA-2jamA:
20.0		 3lxkA-2jamA:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_B_CP6B609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 10 ILE A 278
ALA A 283
PHE A 254
ILE A 125
THR A 282
 None
 1.26A 3qgtB-2jamA:
undetectable		 3qgtB-2jamA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG2_A_IREA1_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		7 / 12 LEU A  29
VAL A  37
ALA A  50
LYS A  52
LEU A  96
MET A  98
LEU A 100
 J60  A1305 (-3.9A)
J60  A1305 (-4.8A)
J60  A1305 (-3.3A)
EDO  A1304 ( 2.9A)
None
EDO  A1304 (-4.6A)
J60  A1305 (-4.4A)
 0.67A 3ug2A-2jamA:
16.6		 3ug2A-2jamA:
27.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 11 ILE A 209
THR A 210
VAL A 128
LEU A 106
TYR A 152
 None
 1.11A 4g1bB-2jamA:
undetectable		 4g1bB-2jamA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 10 ILE A 278
ALA A 283
PHE A 254
ILE A 125
THR A 282
 None
 1.24A 4g8zX-2jamA:
undetectable		 4g8zX-2jamA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 10 ILE A 278
ALA A 283
PHE A 254
ILE A 125
THR A 282
 None
 1.21A 4km0A-2jamA:
undetectable		 4km0A-2jamA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 12 PHE A 300
ASN A 149
ILE A 161
PHE A 107
LEU A 213
 None
 1.21A 4kotA-2jamA:
undetectable		 4kotA-2jamA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 12 PHE A 300
PRO A 147
ASN A 149
PHE A 107
LEU A 213
 None
 1.47A 4kotA-2jamA:
undetectable		 4kotA-2jamA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A206_1
(UNCHARACTERIZED
PROTEIN)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 10 PHE A 300
PRO A 147
ASN A 149
PHE A 107
LEU A 213
 None
 1.44A 4kouA-2jamA:
0.0		 4kouA-2jamA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 12 PHE A 300
PRO A 147
ASN A 149
PHE A 107
LEU A 213
 None
 1.44A 4kowA-2jamA:
undetectable		 4kowA-2jamA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 7 GLY A  30
ALA A  50
ASN A 149
LEU A 151
ASP A 165
 None
J60  A1305 (-3.3A)
None
None
J60  A1305 ( 3.6A)
 1.09A 4ogrE-2jamA:
19.1		 4ogrE-2jamA:
26.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 8 LEU A  29
VAL A  37
LYS A  52
LEU A 151
 J60  A1305 (-3.9A)
J60  A1305 (-4.8A)
EDO  A1304 ( 2.9A)
None
 0.82A 4qrcA-2jamA:
19.4		 4qrcA-2jamA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 10 ALA A  50
LYS A  52
LEU A 100
VAL A 101
LEU A 151
 J60  A1305 (-3.3A)
EDO  A1304 ( 2.9A)
J60  A1305 (-4.4A)
J60  A1305 (-3.9A)
None
 0.85A 4rz7A-2jamA:
6.1		 4rz7A-2jamA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 8 LEU A  29
GLY A  30
VAL A  37
ALA A  50
LEU A 100
 J60  A1305 (-3.9A)
None
J60  A1305 (-4.8A)
J60  A1305 (-3.3A)
J60  A1305 (-4.4A)
 0.38A 4zauA-2jamA:
18.7		 4zauA-2jamA:
27.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 7 LEU A 259
PRO A 219
ILE A 212
LEU A 213
 None
 1.00A 5fxtA-2jamA:
undetectable		 5fxtA-2jamA:
24.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 7 GLY A  30
GLY A  32
PHE A  34
LYS A  52
 None
None
None
EDO  A1304 ( 2.9A)
 0.49A 5izfA-2jamA:
19.6		 5izfA-2jamA:
30.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 7 GLY A  30
GLY A  32
PHE A  34
VAL A  37
 None
None
None
J60  A1305 (-4.8A)
 0.26A 5izjB-2jamA:
20.1		 5izjB-2jamA:
30.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IZJ_G_AZ1G2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 7 GLY A  30
GLY A  32
PHE A  34
VAL A  37
LYS A  52
 None
None
None
J60  A1305 (-4.8A)
EDO  A1304 ( 2.9A)
 0.33A 5izjA-2jamA:
20.0		 5izjA-2jamA:
30.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J5X_B_AZ1B2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAL-DAR-DAR-
DAR-DAR)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 7 GLY A  30
GLY A  32
VAL A  37
LYS A  52
 None
None
J60  A1305 (-4.8A)
EDO  A1304 ( 2.9A)
 0.31A 5j5xA-2jamA:
19.7		 5j5xA-2jamA:
30.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N3H_A_NCAA401_0
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		6 / 10 LEU A  29
VAL A  37
ALA A  50
VAL A  82
MET A  98
VAL A 101
 J60  A1305 (-3.9A)
J60  A1305 (-4.8A)
J60  A1305 (-3.3A)
J60  A1305 ( 4.7A)
EDO  A1304 (-4.6A)
J60  A1305 (-3.9A)
 0.68A 5n3hA-2jamA:
20.1		 5n3hA-2jamA:
30.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 4 VAL A  82
LEU A 100
ASN A 149
ASP A 165
 J60  A1305 ( 4.7A)
J60  A1305 (-4.4A)
None
J60  A1305 ( 3.6A)
 1.16A 5vcyA-2jamA:
19.1		 5vcyA-2jamA:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_A_1E8A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		6 / 12 LEU A  29
GLY A  30
VAL A  37
ALA A  50
LYS A  52
LEU A  96
 J60  A1305 (-3.9A)
None
J60  A1305 (-4.8A)
J60  A1305 (-3.3A)
EDO  A1304 ( 2.9A)
None
 0.54A 5yu9A-2jamA:
16.1		 5yu9A-2jamA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 4 LEU A 273
ASP A 279
GLN A 126
VAL A  72
 None
 1.34A 6bzoF-2jamA:
undetectable		 6bzoF-2jamA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 9 VAL A  37
VAL A  82
LEU A  29
LEU A 100
THR A 164
 J60  A1305 (-4.8A)
J60  A1305 ( 4.7A)
J60  A1305 (-3.9A)
J60  A1305 (-4.4A)
J60  A1305 ( 4.4A)
 1.28A 6czmA-2jamA:
undetectable
6czmB-2jamA:
undetectable		 6czmA-2jamA:
22.05
6czmB-2jamA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 9 VAL A  37
VAL A  82
LEU A  29
LEU A 100
THR A 164
 J60  A1305 (-4.8A)
J60  A1305 ( 4.7A)
J60  A1305 (-3.9A)
J60  A1305 (-4.4A)
J60  A1305 ( 4.4A)
 1.30A 6czmB-2jamA:
undetectable
6czmC-2jamA:
undetectable		 6czmB-2jamA:
22.05
6czmC-2jamA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 8 LEU A 100
THR A 164
VAL A  37
VAL A  82
LEU A  29
 J60  A1305 (-4.4A)
J60  A1305 ( 4.4A)
J60  A1305 (-4.8A)
J60  A1305 ( 4.7A)
J60  A1305 (-3.9A)
 1.28A 6czmD-2jamA:
undetectable
6czmF-2jamA:
undetectable		 6czmD-2jamA:
22.05
6czmF-2jamA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 9 VAL A  37
VAL A  82
LEU A  29
LEU A 100
THR A 164
 J60  A1305 (-4.8A)
J60  A1305 ( 4.7A)
J60  A1305 (-3.9A)
J60  A1305 (-4.4A)
J60  A1305 ( 4.4A)
 1.30A 6czmD-2jamA:
undetectable
6czmE-2jamA:
undetectable		 6czmD-2jamA:
22.05
6czmE-2jamA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		5 / 10 VAL A  37
VAL A  82
LEU A  29
LEU A 100
THR A 164
 J60  A1305 (-4.8A)
J60  A1305 ( 4.7A)
J60  A1305 (-3.9A)
J60  A1305 (-4.4A)
J60  A1305 ( 4.4A)
 1.29A 6czmE-2jamA:
undetectable
6czmF-2jamA:
undetectable		 6czmE-2jamA:
22.05
6czmF-2jamA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		3 / 3 LEU A 213
ASN A  80
LEU A 145
 None
 0.67A 6exiA-2jamA:
undetectable		 6exiA-2jamA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 2jam CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1G
(Homo
sapiens) 		4 / 7 ILE A 255
LEU A 258
VAL A 128
LEU A 145
 None
 0.72A 6g9bA-2jamA:
undetectable
6g9bB-2jamA:
undetectable		 6g9bA-2jamA:
15.49
6g9bB-2jamA:
15.06