SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2jau 5'(3')-DEOXYRIBONUCL
EOTIDASE
(Homo
sapiens) 		4 / 7 SER A  78
PHE A  75
PHE A  49
LEU A 108
 ATM  A1230 (-3.6A)
ATM  A1230 (-4.9A)
ATM  A1230 (-4.3A)
None
 1.13A 1qcaA-2jauA:
undetectable		 1qcaA-2jauA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 2jau 5'(3')-DEOXYRIBONUCL
EOTIDASE
(Homo
sapiens) 		3 / 3 ASP A 171
PHE A 127
ASN A 123
 None
 0.55A 1sg9B-2jauA:
undetectable		 1sg9B-2jauA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 2jau 5'(3')-DEOXYRIBONUCL
EOTIDASE
(Homo
sapiens) 		3 / 3 LEU A  36
ASN A 123
ARG A 226
 None
 0.98A 2qhfA-2jauA:
undetectable		 2qhfA-2jauA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1480_0
(MJ0495-LIKE PROTEIN)		 2jau 5'(3')-DEOXYRIBONUCL
EOTIDASE
(Homo
sapiens) 		4 / 4 LYS A  91
GLU A  97
ILE A  93
SER A  89
 None
 1.36A 4ac9C-2jauA:
3.3		 4ac9C-2jauA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 2jau 5'(3')-DEOXYRIBONUCL
EOTIDASE
(Homo
sapiens) 		4 / 5 LEU A 172
TRP A 189
ILE A 180
ASN A 199
 None
 1.41A 4i00A-2jauA:
undetectable		 4i00A-2jauA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2jau 5'(3')-DEOXYRIBONUCL
EOTIDASE
(Homo
sapiens) 		5 / 10 ALA A 119
VAL A 126
VAL A 147
PHE A 151
GLN A 158
 None
 0.92A 5nukA-2jauA:
undetectable		 5nukA-2jauA:
15.98