SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jbr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		4 / 4 GLY A 172
SER A 220
VAL A  64
LEU A 117
 None
 1.35A 1yajB-2jbrA:
undetectable		 1yajB-2jbrA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		4 / 5 ALA A 104
ILE A 277
ILE A 215
ASP A 389
 None
 0.99A 2h4jA-2jbrA:
undetectable		 2h4jA-2jbrA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		3 / 3 ARG A 385
GLU A 279
SER A 381
 None
 0.85A 2xkkA-2jbrA:
undetectable
2xkkC-2jbrA:
undetectable		 2xkkA-2jbrA:
22.02
2xkkC-2jbrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		5 / 12 SER A 170
LEU A 116
ILE A 215
MET A 392
LEU A 223
 None
 1.45A 2xkwA-2jbrA:
0.0		 2xkwA-2jbrA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		4 / 7 PRO A 231
PHE A 183
ILE A 161
GLY A 197
 None
 0.75A 2y7kA-2jbrA:
undetectable		 2y7kA-2jbrA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		4 / 4 LEU A 324
ARG A 351
LEU A 408
ALA A 355
 None
 1.13A 3b9mA-2jbrA:
undetectable		 3b9mA-2jbrA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		4 / 8 THR A 143
GLY A 172
ALA A 113
ILE A 100
 None
 0.85A 3jusB-2jbrA:
undetectable		 3jusB-2jbrA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		3 / 3 SER A 171
SER A 170
HIS A 175
 None
 0.66A 3mzeA-2jbrA:
0.9		 3mzeA-2jbrA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		3 / 3 SER A 220
SER A 170
HIS A 175
 None
 0.73A 3mzeA-2jbrA:
0.9		 3mzeA-2jbrA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		5 / 12 CYH A 361
LEU A 324
ARG A 322
THR A 352
LEU A 275
 None
 1.23A 3okxA-2jbrA:
undetectable		 3okxA-2jbrA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		4 / 6 ILE A  44
LEU A  77
PHE A  96
GLY A 269
 None
 1.01A 3sj1X-2jbrA:
undetectable		 3sj1X-2jbrA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		5 / 12 GLY A 276
GLY A 105
SER A 271
GLU A 283
ALA A 278
 None
 1.39A 3t7sC-2jbrA:
undetectable		 3t7sC-2jbrA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		3 / 3 TYR A 398
MET A 360
LEU A 324
 None
 0.95A 3vw1D-2jbrA:
1.5		 3vw1D-2jbrA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		5 / 11 GLY A 197
ALA A 149
VAL A 181
PRO A 231
ILE A 161
 None
 1.36A 4j4vA-2jbrA:
undetectable		 4j4vA-2jbrA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		4 / 5 PHE A 196
TYR A 262
THR A 119
ILE A 180
 None
 1.24A 4jx1E-2jbrA:
undetectable		 4jx1E-2jbrA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		5 / 8 VAL A 358
ILE A 362
VAL A 273
HIS A 396
PHE A 270
 None
 1.41A 5l94A-2jbrA:
undetectable		 5l94A-2jbrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		3 / 3 LYS A 256
LEU A 337
ARG A 333
 None
 0.61A 5yw0A-2jbrA:
undetectable		 5yw0A-2jbrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT
(Acinetobacter
baumannii) 		3 / 3 TYR A 398
HIS A 396
PHE A 270
 None
 1.07A 6esmA-2jbrA:
undetectable		 6esmA-2jbrA:
12.43