SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jch'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GHM_A_CEDA1_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	ALA A 459 SER A 460 LYS A 463 SER A 516 ASN A 518 LYS A 651 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 ( 4.0A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.58A	1ghmA-2jchA: 14.8	1ghmA-2jchA: 15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I2W_A_CFXA1300_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	8 / 12	ALA A 459 SER A 460 LYS A 463 SER A 516 ASN A 518 ASN A 656 LYS A 651 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 ( 4.0A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 (-4.8A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	1.03A	1i2wA-2jchA: 15.1	1i2wA-2jchA: 18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I2W_A_CFXA1300_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	8 / 12	ALA A 459 SER A 460 LYS A 463 SER A 516 ASN A 518 THR A 629 LYS A 651 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 ( 4.0A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.67A	1i2wA-2jchA: 15.1	1i2wA-2jchA: 18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I2W_B_CFXB2300_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	ALA A 459 SER A 460 LYS A 463 SER A 516 ASN A 518 ASN A 656 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 ( 4.0A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 (-4.8A) PL7 A1793 (-3.3A)	1.03A	1i2wB-2jchA: 15.1	1i2wB-2jchA: 18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I2W_B_CFXB2300_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	ALA A 459 SER A 460 LYS A 463 SER A 516 ASN A 518 THR A 629 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 ( 4.0A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.61A	1i2wB-2jchA: 15.1	1i2wB-2jchA: 18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JU6_A_LYAA317_1 (THYMIDYLATE SYNTHASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 11	ILE A 482 ASN A 485 LEU A 509 GLY A 510 ALA A 521	None	1.35A	1ju6A-2jchA: undetectable	1ju6A-2jchA: 17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JU6_C_LYAC315_1 (THYMIDYLATE SYNTHASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 10	ILE A 482 ASN A 485 LEU A 509 GLY A 510 ALA A 521	None	1.35A	1ju6C-2jchA: undetectable	1ju6C-2jchA: 17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JU6_D_LYAD315_1 (THYMIDYLATE SYNTHASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 11	ILE A 482 ASN A 485 LEU A 509 GLY A 510 ALA A 521	None	1.35A	1ju6D-2jchA: undetectable	1ju6D-2jchA: 17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDS_A_SAMA5635_0 (PROTEIN RDMB)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 12	GLY A 557 GLY A 558 GLY A 559 ASN A 660 TRP A 662	None	1.04A	1xdsA-2jchA: undetectable	1xdsA-2jchA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDS_B_SAMB9635_0 (PROTEIN RDMB)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 12	GLY A 557 GLY A 558 GLY A 559 ASN A 660 TRP A 662	None	1.00A	1xdsB-2jchA: undetectable	1xdsB-2jchA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YMX_A_CFXA1001_1 (BETA-LACTAMASE CTX-M-9)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 LYS A 463 SER A 516 ASN A 518 THR A 629 LYS A 651 GLY A 653	PL7 A1793 (-1.4A) PL7 A1793 ( 4.0A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.74A	1ymxA-2jchA: 15.8	1ymxA-2jchA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YMX_B_CFXB1002_1 (BETA-LACTAMASE CTX-M-9)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	6 / 12	SER A 460 LYS A 463 SER A 516 ASN A 518 LYS A 651 GLY A 653	PL7 A1793 (-1.4A) PL7 A1793 ( 4.0A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.63A	1ymxB-2jchA: 15.9	1ymxB-2jchA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2LBD_A_REAA500_1 (RETINOIC ACID RECEPTOR GAMMA)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 12	LEU A 476 MET A 477 ILE A 772 GLY A 469 LEU A 466	None	1.00A	2lbdA-2jchA: undetectable	2lbdA-2jchA: 16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6F_C_010C6_0 (INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE N-[(5-METHYLISOXAZOL -3-YL)CARBONYL]ALANY L-L-VALYL-N~1~-((1R, 2Z)-4-(BENZYLOXY)-4- OXO-1-{[(3R)-2-OXOPY RROLIDIN-3-YL]METHYL }BUT-2-ENYL)-L-LEUCI NAMIDE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	3 / 3	ASN A 660 LEU A 684 HIS A 678	None	0.84A	2q6fB-2jchA: undetectable	2q6fB-2jchA: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AVP_A_MV2A313_1 (PANTOTHENATE KINASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	4 / 7	HIS A 567 LEU A 620 TYR A 608 ILE A 470	None	1.02A	3avpA-2jchA: undetectable	3avpA-2jchA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HLW_A_CE3A301_1 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	LYS A 463 TYR A 498 SER A 516 ASN A 518 THR A 629 LYS A 651 GLY A 653	PL7 A1793 ( 4.0A) PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.76A	3hlwA-2jchA: 15.8	3hlwA-2jchA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HLW_B_CE3B302_1 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	TYR A 498 SER A 516 ASN A 518 THR A 629 LYS A 651 THR A 652 GLY A 653	PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A)	0.69A	3hlwB-2jchA: 15.4	3hlwB-2jchA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MZE_A_CFXA364_1 (D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACA)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	ALA A 459 SER A 460 LYS A 463 ASN A 518 THR A 652 GLY A 653 THR A 655	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 ( 4.0A) PL7 A1793 (-3.2A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) None	0.87A	3mzeA-2jchA: 13.1	3mzeA-2jchA: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NY4_A_SMXA308_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.63A	3ny4A-2jchA: 15.3	3ny4A-2jchA: 17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU7_A_SAMA300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 12	TYR A 468 ALA A 471 GLY A 469 GLY A 478 MET A 616	None	1.25A	3ou7A-2jchA: undetectable	3ou7A-2jchA: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU7_D_SAMD300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 12	TYR A 468 ALA A 471 GLY A 469 GLY A 478 MET A 616	None	1.23A	3ou7D-2jchA: undetectable	3ou7D-2jchA: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SH8_A_CEDA1_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	8 / 12	ALA A 459 SER A 460 TYR A 498 SER A 516 ASN A 518 LYS A 651 THR A 652 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A)	0.64A	3sh8A-2jchA: 15.6	3sh8A-2jchA: 18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SH8_B_CEDB1_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	ALA A 459 SER A 460 LYS A 463 SER A 516 ASN A 518 LYS A 651 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 ( 4.0A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.60A	3sh8B-2jchA: 15.3	3sh8B-2jchA: 18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EUZ_A_MEMA401_1 (CARBAPENEM-HYDROLIZI NG BETA-LACTAMASE SFC-1)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	8 / 12	LYS A 463 SER A 516 ASN A 518 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 ( 4.0A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.83A	4euzA-2jchA: 15.6	4euzA-2jchA: 19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGK_A_0TXA302_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	4 / 7	GLY A 505 TYR A 486 ASN A 781 GLU A 511	None	1.04A	4fgkB-2jchA: undetectable	4fgkB-2jchA: 16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N9K_A_CEDA301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	8 / 12	ALA A 459 SER A 460 TYR A 498 SER A 516 ASN A 518 LYS A 651 THR A 652 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A)	0.61A	4n9kA-2jchA: 5.0	4n9kA-2jchA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N9K_B_CEDB301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	ALA A 459 SER A 460 SER A 516 ASN A 518 LYS A 651 THR A 652 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A)	0.57A	4n9kB-2jchA: 5.1	4n9kB-2jchA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PM5_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	TYR A 498 SER A 516 ASN A 518 THR A 629 LYS A 651 THR A 652 GLY A 653	PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A)	0.83A	4pm5A-2jchA: 15.5	4pm5A-2jchA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PM7_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	LYS A 463 TYR A 498 SER A 516 ASN A 518 THR A 629 LYS A 651 GLY A 653	PL7 A1793 ( 4.0A) PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.89A	4pm7A-2jchA: 15.8	4pm7A-2jchA: 17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PM9_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	TYR A 498 SER A 516 ASN A 518 THR A 629 LYS A 651 THR A 652 GLY A 653	PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A)	0.81A	4pm9A-2jchA: 15.8	4pm9A-2jchA: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_D_29SD601_2 (ESTROGEN RECEPTOR)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	3 / 3	LEU A 620 ASP A 647 ILE A 472	None	0.70A	4xi3D-2jchA: undetectable	4xi3D-2jchA: 15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DNU_A_BEZA319_0 (SHKAI2IB)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	4 / 5	GLN A 474 ILE A 470 ILE A 472 TYR A 538	None	1.25A	5dnuA-2jchA: undetectable	5dnuA-2jchA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FCT_A_C2FA402_0 (THYMIDYLATE SYNTHASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 11	ILE A 482 ASN A 485 LEU A 509 GLY A 510 ALA A 521	None	1.33A	5fctA-2jchA: undetectable	5fctA-2jchA: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GHY_A_CEDA301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	6 / 12	ALA A 459 SER A 460 SER A 516 ASN A 518 LYS A 651 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.60A	5ghyA-2jchA: 15.4	5ghyA-2jchA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GHY_B_CEDB301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	6 / 12	ALA A 459 SER A 460 SER A 516 ASN A 518 LYS A 651 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.57A	5ghyB-2jchA: 5.3	5ghyB-2jchA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GHZ_A_CEDA301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	8 / 11	ALA A 459 SER A 460 TYR A 498 SER A 516 ASN A 518 LYS A 651 THR A 652 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A)	0.60A	5ghzA-2jchA: 15.3	5ghzA-2jchA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GHZ_B_CEDB301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	8 / 10	ALA A 459 SER A 460 TYR A 498 SER A 516 ASN A 518 LYS A 651 THR A 652 GLY A 653	PL7 A1793 (-3.5A) PL7 A1793 (-1.4A) PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A)	0.60A	5ghzB-2jchA: 5.1	5ghzB-2jchA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N1T_W_CUW201_0 (COPC)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	3 / 3	HIS A 678 ASP A 680 HIS A 682	None	0.92A	5n1tW-2jchA: undetectable	5n1tW-2jchA: 12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZX_A_9F2A1102_1 (DNA CROSS-LINK REPAIR 1A PROTEIN)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	4 / 8	THR A 667 GLN A 705 ILE A 711 GLY A 713	None	0.94A	5nzxA-2jchA: undetectable	5nzxA-2jchA: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NZY_A_CE3A1102_1 (DNA CROSS-LINK REPAIR 1A PROTEIN)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	4 / 7	THR A 667 GLN A 705 ILE A 711 GLY A 713	None	0.92A	5nzyA-2jchA: undetectable	5nzyA-2jchA: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W4Z_A_RBFA502_1 (RIBOFLAVIN LYASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	5 / 12	ALA A 646 ALA A 644 PHE A 717 ALA A 575 PHE A 632	None	0.91A	5w4zA-2jchA: undetectable	5w4zA-2jchA: 7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_B_9F2B400_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.49A	6b5yB-2jchA: 5.3	6b5yB-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_D_9F2D400_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.50A	6b5yD-2jchA: 15.3	6b5yD-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_B_9F2B301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.51A	6b68B-2jchA: 15.3	6b68B-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_D_9F2D400_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	6 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.56A	6b68D-2jchA: 15.3	6b68D-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_B_9F2B301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.54A	6b69A-2jchA: 15.3 6b69B-2jchA: 15.3	6b69A-2jchA: 8.06 6b69B-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_D_9F2D301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.54A	6b69D-2jchA: 5.4	6b69D-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_B_9F2B301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.53A	6b6aB-2jchA: 15.3	6b6aB-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_D_9F2D301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	6 / 12	SER A 460 SER A 516 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.54A	6b6aD-2jchA: 15.2	6b6aD-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6C_A_9F2A301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	6 / 12	SER A 460 SER A 516 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.59A	6b6cA-2jchA: 15.3	6b6cA-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6D_A_9F2A302_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.68A	6b6dA-2jchA: 15.3	6b6dA-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6E_A_9F2A302_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	7 / 12	SER A 460 SER A 516 THR A 629 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.60A	6b6eA-2jchA: 15.5	6b6eA-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6F_A_9F2A301_1 (BETA-LACTAMASE)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	6 / 12	SER A 460 SER A 516 LYS A 651 THR A 652 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.9A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.66A	6b6fA-2jchA: 15.2	6b6fA-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C79_A_CE3A301_1 (BETA-LACTAMASE TOHO-1)	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	6 / 12	TYR A 498 SER A 516 ASN A 518 THR A 629 LYS A 651 GLY A 653	PL7 A1793 (-4.3A) PL7 A1793 (-3.0A) PL7 A1793 (-3.2A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A)	0.67A	6c79A-2jchA: 15.7	6c79A-2jchA: 7.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GHM_A_CEDA1_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"ALA A 459;SER A 460;LYS A 463;SER A 516;ASN A 518;LYS A 651;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 ( 4.0A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.58A","1ghmA-2jchA:14.8","1ghmA-2jchA:15.21"],["1I2W_A_CFXA1300_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",8,"ALA A 459;SER A 460;LYS A 463;SER A 516;ASN A 518;ASN A 656;LYS A 651;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 ( 4.0A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 (-4.8A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","1.03A","1i2wA-2jchA:15.1","1i2wA-2jchA:18.51"],["1I2W_A_CFXA1300_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",8,"ALA A 459;SER A 460;LYS A 463;SER A 516;ASN A 518;THR A 629;LYS A 651;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 ( 4.0A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.67A","1i2wA-2jchA:15.1","1i2wA-2jchA:18.51"],["1I2W_B_CFXB2300_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"ALA A 459;SER A 460;LYS A 463;SER A 516;ASN A 518;ASN A 656;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 ( 4.0A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 (-4.8A);PL7 A1793 (-3.3A)","1.03A","1i2wB-2jchA:15.1","1i2wB-2jchA:18.51"],["1I2W_B_CFXB2300_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"ALA A 459;SER A 460;LYS A 463;SER A 516;ASN A 518;THR A 629;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 ( 4.0A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.61A","1i2wB-2jchA:15.1","1i2wB-2jchA:18.51"],["1JU6_A_LYAA317_1","THYMIDYLATE SYNTHASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"ILE A 482;ASN A 485;LEU A 509;GLY A 510;ALA A 521","None","1.35A","1ju6A-2jchA:undetectable","1ju6A-2jchA:17.29"],["1JU6_C_LYAC315_1","THYMIDYLATE SYNTHASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"ILE A 482;ASN A 485;LEU A 509;GLY A 510;ALA A 521","None","1.35A","1ju6C-2jchA:undetectable","1ju6C-2jchA:17.29"],["1JU6_D_LYAD315_1","THYMIDYLATE SYNTHASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"ILE A 482;ASN A 485;LEU A 509;GLY A 510;ALA A 521","None","1.35A","1ju6D-2jchA:undetectable","1ju6D-2jchA:17.29"],["1XDS_A_SAMA5635_0","PROTEIN RDMB","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"GLY A 557;GLY A 558;GLY A 559;ASN A 660;TRP A 662","None","1.04A","1xdsA-2jchA:undetectable","1xdsA-2jchA:19.53"],["1XDS_B_SAMB9635_0","PROTEIN RDMB","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"GLY A 557;GLY A 558;GLY A 559;ASN A 660;TRP A 662","None","1.00A","1xdsB-2jchA:undetectable","1xdsB-2jchA:19.53"],["1YMX_A_CFXA1001_1","BETA-LACTAMASE CTX-M-9","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;LYS A 463;SER A 516;ASN A 518;THR A 629;LYS A 651;GLY A 653","PL7 A1793 (-1.4A);PL7 A1793 ( 4.0A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.74A","1ymxA-2jchA:15.8","1ymxA-2jchA:17.78"],["1YMX_B_CFXB1002_1","BETA-LACTAMASE CTX-M-9","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",6,"SER A 460;LYS A 463;SER A 516;ASN A 518;LYS A 651;GLY A 653","PL7 A1793 (-1.4A);PL7 A1793 ( 4.0A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.63A","1ymxB-2jchA:15.9","1ymxB-2jchA:17.78"],["2LBD_A_REAA500_1","RETINOIC ACID RECEPTOR GAMMA","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"LEU A 476;MET A 477;ILE A 772;GLY A 469;LEU A 466","None","1.00A","2lbdA-2jchA:undetectable","2lbdA-2jchA:16.74"],["2Q6F_C_010C6_0","INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE;N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",3,"ASN A 660;LEU A 684;HIS A 678","None","0.84A","2q6fB-2jchA:undetectable","2q6fB-2jchA:19.56"],["3AVP_A_MV2A313_1","PANTOTHENATE KINASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",4,"HIS A 567;LEU A 620;TYR A 608;ILE A 470","None","1.02A","3avpA-2jchA:undetectable","3avpA-2jchA:18.75"],["3HLW_A_CE3A301_1","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"LYS A 463;TYR A 498;SER A 516;ASN A 518;THR A 629;LYS A 651;GLY A 653","PL7 A1793 ( 4.0A);PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.76A","3hlwA-2jchA:15.8","3hlwA-2jchA:17.68"],["3HLW_B_CE3B302_1","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"TYR A 498;SER A 516;ASN A 518;THR A 629;LYS A 651;THR A 652;GLY A 653","PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A)","0.69A","3hlwB-2jchA:15.4","3hlwB-2jchA:17.68"],["3MZE_A_CFXA364_1","D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACA","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"ALA A 459;SER A 460;LYS A 463;ASN A 518;THR A 652;GLY A 653;THR A 655","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 ( 4.0A);PL7 A1793 (-3.2A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);None","0.87A","3mzeA-2jchA:13.1","3mzeA-2jchA:21.01"],["3NY4_A_SMXA308_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;SER A 516;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.63A","3ny4A-2jchA:15.3","3ny4A-2jchA:17.74"],["3OU7_A_SAMA300_0","SAM-DEPENDENT METHYLTRANSFERASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"TYR A 468;ALA A 471;GLY A 469;GLY A 478;MET A 616","None","1.25A","3ou7A-2jchA:undetectable","3ou7A-2jchA:16.39"],["3OU7_D_SAMD300_0","SAM-DEPENDENT METHYLTRANSFERASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"TYR A 468;ALA A 471;GLY A 469;GLY A 478;MET A 616","None","1.23A","3ou7D-2jchA:undetectable","3ou7D-2jchA:16.39"],["3SH8_A_CEDA1_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",8,"ALA A 459;SER A 460;TYR A 498;SER A 516;ASN A 518;LYS A 651;THR A 652;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A)","0.64A","3sh8A-2jchA:15.6","3sh8A-2jchA:18.19"],["3SH8_B_CEDB1_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"ALA A 459;SER A 460;LYS A 463;SER A 516;ASN A 518;LYS A 651;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 ( 4.0A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.60A","3sh8B-2jchA:15.3","3sh8B-2jchA:18.19"],["4EUZ_A_MEMA401_1","CARBAPENEM-HYDROLIZING BETA-LACTAMASE SFC-1","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",8,"LYS A 463;SER A 516;ASN A 518;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 ( 4.0A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.83A","4euzA-2jchA:15.6","4euzA-2jchA:19.11"],["4FGK_A_0TXA302_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",4,"GLY A 505;TYR A 486;ASN A 781;GLU A 511","None","1.04A","4fgkB-2jchA:undetectable","4fgkB-2jchA:16.41"],["4N9K_A_CEDA301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",8,"ALA A 459;SER A 460;TYR A 498;SER A 516;ASN A 518;LYS A 651;THR A 652;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A)","0.61A","4n9kA-2jchA:5.0","4n9kA-2jchA:18.33"],["4N9K_B_CEDB301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"ALA A 459;SER A 460;SER A 516;ASN A 518;LYS A 651;THR A 652;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A)","0.57A","4n9kB-2jchA:5.1","4n9kB-2jchA:18.33"],["4PM5_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"TYR A 498;SER A 516;ASN A 518;THR A 629;LYS A 651;THR A 652;GLY A 653","PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A)","0.83A","4pm5A-2jchA:15.5","4pm5A-2jchA:17.68"],["4PM7_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"LYS A 463;TYR A 498;SER A 516;ASN A 518;THR A 629;LYS A 651;GLY A 653","PL7 A1793 ( 4.0A);PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.89A","4pm7A-2jchA:15.8","4pm7A-2jchA:17.96"],["4PM9_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"TYR A 498;SER A 516;ASN A 518;THR A 629;LYS A 651;THR A 652;GLY A 653","PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A)","0.81A","4pm9A-2jchA:15.8","4pm9A-2jchA:17.06"],["4XI3_D_29SD601_2","ESTROGEN RECEPTOR","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",3,"LEU A 620;ASP A 647;ILE A 472","None","0.70A","4xi3D-2jchA:undetectable","4xi3D-2jchA:15.59"],["5DNU_A_BEZA319_0","SHKAI2IB","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",4,"GLN A 474;ILE A 470;ILE A 472;TYR A 538","None","1.25A","5dnuA-2jchA:undetectable","5dnuA-2jchA:18.21"],["5FCT_A_C2FA402_0","THYMIDYLATE SYNTHASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"ILE A 482;ASN A 485;LEU A 509;GLY A 510;ALA A 521","None","1.33A","5fctA-2jchA:undetectable","5fctA-2jchA:18.11"],["5GHY_A_CEDA301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",6,"ALA A 459;SER A 460;SER A 516;ASN A 518;LYS A 651;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.60A","5ghyA-2jchA:15.4","5ghyA-2jchA:18.33"],["5GHY_B_CEDB301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",6,"ALA A 459;SER A 460;SER A 516;ASN A 518;LYS A 651;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.57A","5ghyB-2jchA:5.3","5ghyB-2jchA:18.33"],["5GHZ_A_CEDA301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",8,"ALA A 459;SER A 460;TYR A 498;SER A 516;ASN A 518;LYS A 651;THR A 652;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A)","0.60A","5ghzA-2jchA:15.3","5ghzA-2jchA:18.33"],["5GHZ_B_CEDB301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",8,"ALA A 459;SER A 460;TYR A 498;SER A 516;ASN A 518;LYS A 651;THR A 652;GLY A 653","PL7 A1793 (-3.5A);PL7 A1793 (-1.4A);PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A)","0.60A","5ghzB-2jchA:5.1","5ghzB-2jchA:18.33"],["5N1T_W_CUW201_0","COPC","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",3,"HIS A 678;ASP A 680;HIS A 682","None","0.92A","5n1tW-2jchA:undetectable","5n1tW-2jchA:12.97"],["5NZX_A_9F2A1102_1","DNA CROSS-LINK REPAIR 1A PROTEIN","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",4,"THR A 667;GLN A 705;ILE A 711;GLY A 713","None","0.94A","5nzxA-2jchA:undetectable","5nzxA-2jchA:18.63"],["5NZY_A_CE3A1102_1","DNA CROSS-LINK REPAIR 1A PROTEIN","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",4,"THR A 667;GLN A 705;ILE A 711;GLY A 713","None","0.92A","5nzyA-2jchA:undetectable","5nzyA-2jchA:18.63"],["5W4Z_A_RBFA502_1","RIBOFLAVIN LYASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",5,"ALA A 646;ALA A 644;PHE A 717;ALA A 575;PHE A 632","None","0.91A","5w4zA-2jchA:undetectable","5w4zA-2jchA:7.36"],["6B5Y_B_9F2B400_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;SER A 516;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.49A","6b5yB-2jchA:5.3","6b5yB-2jchA:8.06"],["6B5Y_D_9F2D400_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;SER A 516;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.50A","6b5yD-2jchA:15.3","6b5yD-2jchA:8.06"],["6B68_B_9F2B301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;SER A 516;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.51A","6b68B-2jchA:15.3","6b68B-2jchA:8.06"],["6B68_D_9F2D400_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",6,"SER A 460;SER A 516;THR A 629;LYS A 651;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.56A","6b68D-2jchA:15.3","6b68D-2jchA:8.06"],["6B69_B_9F2B301_1","BETA-LACTAMASE;BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;SER A 516;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.54A","6b69A-2jchA:15.3;6b69B-2jchA:15.3","6b69A-2jchA:8.06;6b69B-2jchA:8.06"],["6B69_D_9F2D301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;SER A 516;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.54A","6b69D-2jchA:5.4","6b69D-2jchA:8.06"],["6B6A_B_9F2B301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;SER A 516;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.53A","6b6aB-2jchA:15.3","6b6aB-2jchA:8.06"],["6B6A_D_9F2D301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",6,"SER A 460;SER A 516;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.54A","6b6aD-2jchA:15.2","6b6aD-2jchA:8.06"],["6B6C_A_9F2A301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",6,"SER A 460;SER A 516;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.59A","6b6cA-2jchA:15.3","6b6cA-2jchA:8.06"],["6B6D_A_9F2A302_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;SER A 516;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.68A","6b6dA-2jchA:15.3","6b6dA-2jchA:8.06"],["6B6E_A_9F2A302_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",7,"SER A 460;SER A 516;THR A 629;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.60A","6b6eA-2jchA:15.5","6b6eA-2jchA:8.06"],["6B6F_A_9F2A301_1","BETA-LACTAMASE","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",6,"SER A 460;SER A 516;LYS A 651;THR A 652;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.9A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.66A","6b6fA-2jchA:15.2","6b6fA-2jchA:8.06"],["6C79_A_CE3A301_1","BETA-LACTAMASE TOHO-1","2jch","PENICILLIN-BINDING PROTEIN 1B","Streptococcus pneumoniae",6,"TYR A 498;SER A 516;ASN A 518;THR A 629;LYS A 651;GLY A 653","PL7 A1793 (-4.3A);PL7 A1793 (-3.0A);PL7 A1793 (-3.2A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A)","0.67A","6c79A-2jchA:15.7","6c79A-2jchA:7.92"]]