SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jd4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 4 ILE A2901
LEU A3041
VAL A3003
ILE A3001
 None
 0.88A 1fm6D-2jd4A:
undetectable		 1fm6D-2jd4A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 7 GLY A2702
SER A2841
HIS A2708
ALA A2864
 None
 0.97A 1gxsA-2jd4A:
undetectable
1gxsB-2jd4A:
undetectable		 1gxsA-2jd4A:
20.00
1gxsB-2jd4A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 7 HIS A3053
LEU A3028
ASP A3040
PHE A2880
 None
 1.21A 1ismB-2jd4A:
undetectable		 1ismB-2jd4A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 8 PHE A2879
TYR A2694
ARG A3022
TYR A2871
 None
 1.45A 1xqlA-2jd4A:
undetectable
1xqlB-2jd4A:
undetectable		 1xqlA-2jd4A:
22.63
1xqlB-2jd4A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 8 TYR A2694
ARG A3022
TYR A2871
PHE A2879
 None
 1.45A 1xqlA-2jd4A:
undetectable
1xqlB-2jd4A:
undetectable		 1xqlA-2jd4A:
22.63
1xqlB-2jd4A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		3 / 3 ARG A2869
GLY A2693
PRO A2692
 None
 0.70A 2hreD-2jd4A:
undetectable		 2hreD-2jd4A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		3 / 3 LEU A2826
PRO A2827
ARG A2833
 None
 0.42A 2qd5A-2jd4A:
undetectable		 2qd5A-2jd4A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 5 VAL A2785
VAL A2798
THR A2730
THR A2787
 None
 1.25A 3bjwG-2jd4A:
undetectable		 3bjwG-2jd4A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 5 VAL A2785
VAL A2798
THR A2730
THR A2787
 None
 1.23A 3bjwD-2jd4A:
undetectable		 3bjwD-2jd4A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 9 ILE A2929
GLY A2912
PHE A3021
THR A2907
GLY A3023
 None
 1.37A 4acaB-2jd4A:
undetectable
4acaC-2jd4A:
undetectable		 4acaB-2jd4A:
22.22
4acaC-2jd4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 12 HIS A2840
HIS A2708
GLY A2824
GLY A2735
HIS A2699
 None
 1.19A 4blvB-2jd4A:
undetectable		 4blvB-2jd4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 12 ASN A2940
ILE A2901
GLY A2926
SER A3014
ILE A2925
 None
 1.23A 4djfA-2jd4A:
undetectable		 4djfA-2jd4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 6 GLY A2892
VAL A2889
GLY A2916
TYR A3002
 None
 0.73A 4dxuA-2jd4A:
undetectable		 4dxuA-2jd4A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_A_ACTA1002_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 5 THR A2797
GLN A2723
GLU A2788
THR A2787
 None
 1.19A 4eahA-2jd4A:
undetectable
4eahE-2jd4A:
undetectable
4eahG-2jd4A:
0.0		 4eahA-2jd4A:
22.10
4eahE-2jd4A:
22.10
4eahG-2jd4A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		3 / 3 LEU A2826
PRO A2827
ARG A2833
 None
 0.72A 4klrB-2jd4A:
undetectable		 4klrB-2jd4A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		4 / 6 GLY A2877
ASP A3040
PRO A2843
HIS A2840
 None
 1.23A 4lajA-2jd4A:
undetectable
4lajB-2jd4A:
undetectable		 4lajA-2jd4A:
20.89
4lajB-2jd4A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 6 THR A2946
ALA A2947
THR A2948
VAL A2983
HIS A2937
 None
 1.43A 5ecoA-2jd4A:
undetectable		 5ecoA-2jd4A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 2jd4 LAMININ SUBUNIT
ALPHA-1
(Mus
musculus) 		5 / 12 ILE A2901
ILE A3001
VAL A3003
LEU A2914
LEU A2965
 None
 1.12A 6ajiA-2jd4A:
undetectable		 6ajiA-2jd4A:
17.90