SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jdf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 2jdf GAMMA CRYSTALLIN B
(Homo
sapiens) 		3 / 3 GLY A 129
TYR A  88
SER A 130
 None
 0.75A 2xatA-2jdfA:
undetectable		 2xatA-2jdfA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 2jdf GAMMA CRYSTALLIN B
(Homo
sapiens) 		5 / 9 PRO A 148
ILE A  81
MET A  43
VAL A 170
ILE A 132
 None
 1.11A 3p4wB-2jdfA:
undetectable		 3p4wB-2jdfA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 2jdf GAMMA CRYSTALLIN B
(Homo
sapiens) 		5 / 10 PRO A 148
ILE A  81
MET A  43
VAL A 170
ILE A 132
 None
 1.12A 3p4wD-2jdfA:
undetectable		 3p4wD-2jdfA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 2jdf GAMMA CRYSTALLIN B
(Homo
sapiens) 		5 / 10 PRO A 148
ILE A  81
MET A  43
VAL A 170
ILE A 132
 None
 1.13A 3p4wE-2jdfA:
undetectable		 3p4wE-2jdfA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 2jdf GAMMA CRYSTALLIN B
(Homo
sapiens) 		4 / 6 GLU A  97
LEU A  98
ARG A  99
ARG A 152
 None
 1.16A 5l6eA-2jdfA:
undetectable
5l6eB-2jdfA:
undetectable		 5l6eA-2jdfA:
20.37
5l6eB-2jdfA:
18.21