SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jel'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	2jel	JEL42 FAB FRAGMENT (Mus musculus)	4 / 4	THR H 116 PRO H 118 THR H 117 PRO H 149	None	1.34A	1dsdC-2jelH: undetectable	1dsdC-2jelH: 6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC2_0 (ACTINOMYCIN D)	2jel	JEL42 FAB FRAGMENT (Mus musculus)	4 / 4	THR H 117 PRO H 149 THR H 116 PRO H 118	None	1.27A	1dsdC-2jelH: undetectable	1dsdC-2jelH: 6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	2jel	JEL42 FAB FRAGMENT (Mus musculus)	4 / 4	THR H 116 PRO H 118 THR H 117 PRO H 149	None	1.34A	1dsdC-2jelH: undetectable	1dsdC-2jelH: 6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSD_C_DVAC8_0 (ACTINOMYCIN D)	2jel	JEL42 FAB FRAGMENT (Mus musculus)	4 / 4	THR H 117 PRO H 149 THR H 116 PRO H 118	None	1.27A	1dsdC-2jelH: undetectable	1dsdC-2jelH: 6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDT_A_ACTA409_0 (FAD:PROTEIN FMN TRANSFERASE)	2jel	JEL42 FAB FRAGMENT (Mus musculus)	4 / 5	VAL H 18 ILE H 20 VAL H 109 THR H 107	None	0.62A	4xdtA-2jelH: undetectable	4xdtA-2jelH: 19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DNV_A_BEZA304_0 (SHKAI2IB)	2jel	JEL42 FAB FRAGMENT (Mus musculus)	4 / 5	GLN H 39 HIS H 41 ILE H 89 TYR H 91	None	1.19A	5dnvA-2jelH: undetectable	5dnvA-2jelH: 22.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","2jel","JEL42 FAB FRAGMENT","Mus musculus",4,"THR H 116;PRO H 118;THR H 117;PRO H 149","None","1.34A","1dsdC-2jelH:undetectable","1dsdC-2jelH:6.38"],["1DSD_C_DVAC2_0","ACTINOMYCIN D","2jel","JEL42 FAB FRAGMENT","Mus musculus",4,"THR H 117;PRO H 149;THR H 116;PRO H 118","None","1.27A","1dsdC-2jelH:undetectable","1dsdC-2jelH:6.38"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","2jel","JEL42 FAB FRAGMENT","Mus musculus",4,"THR H 116;PRO H 118;THR H 117;PRO H 149","None","1.34A","1dsdC-2jelH:undetectable","1dsdC-2jelH:6.38"],["1DSD_C_DVAC8_0","ACTINOMYCIN D","2jel","JEL42 FAB FRAGMENT","Mus musculus",4,"THR H 117;PRO H 149;THR H 116;PRO H 118","None","1.27A","1dsdC-2jelH:undetectable","1dsdC-2jelH:6.38"],["4XDT_A_ACTA409_0","FAD:PROTEIN FMN TRANSFERASE","2jel","JEL42 FAB FRAGMENT","Mus musculus",4,"VAL H  18;ILE H  20;VAL H 109;THR H 107","None","0.62A","4xdtA-2jelH:undetectable","4xdtA-2jelH:19.71"],["5DNV_A_BEZA304_0","SHKAI2IB","2jel","JEL42 FAB FRAGMENT","Mus musculus",4,"GLN H  39;HIS H  41;ILE H  89;TYR H  91","None","1.19A","5dnvA-2jelH:undetectable","5dnvA-2jelH:22.57"]]