SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jem'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 2jem ENDO-BETA-1,4-GLUCAN
ASE
(Bacillus
licheniformis) 		4 / 5 THR A 259
GLY A 105
LYS A  42
TYR A  46
 None
 1.24A 1gtiF-2jemA:
undetectable		 1gtiF-2jemA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2jem ENDO-BETA-1,4-GLUCAN
ASE
(Bacillus
licheniformis) 		5 / 12 LEU A 160
TYR A  89
ILE A 251
MET A  73
PHE A 240
 None
 1.16A 1xoqA-2jemA:
undetectable		 1xoqA-2jemA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2jem ENDO-BETA-1,4-GLUCAN
ASE
(Bacillus
licheniformis) 		5 / 12 LEU A 160
TYR A  89
ILE A 251
MET A  73
PHE A 240
 None
 1.11A 1xoqB-2jemA:
undetectable		 1xoqB-2jemA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2jem ENDO-BETA-1,4-GLUCAN
ASE
(Bacillus
licheniformis) 		4 / 7 LEU A 140
THR A 232
LEU A 112
THR A 153
 None
 0.94A 4z90A-2jemA:
undetectable
4z90B-2jemA:
undetectable
4z90C-2jemA:
undetectable
4z90D-2jemA:
undetectable
4z90E-2jemA:
undetectable		 4z90A-2jemA:
21.54
4z90B-2jemA:
21.54
4z90C-2jemA:
21.54
4z90D-2jemA:
21.54
4z90E-2jemA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 2jem ENDO-BETA-1,4-GLUCAN
ASE
(Bacillus
licheniformis) 		3 / 3 ASP A 257
SER A  94
TYR A  46
 None
 0.70A 5glmA-2jemA:
undetectable		 5glmA-2jemA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2jem ENDO-BETA-1,4-GLUCAN
ASE
(Bacillus
licheniformis) 		5 / 8 VAL A 258
ILE A 138
ILE A 215
ILE A 158
SER A 123
 None
 1.38A 5numA-2jemA:
undetectable		 5numA-2jemA:
16.07