SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jep'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		4 / 7 GLY A 132
SER A  91
TRP A  65
ALA A  64
 None
 0.83A 1gxsA-2jepA:
undetectable
1gxsB-2jepA:
undetectable		 1gxsA-2jepA:
17.41
1gxsB-2jepA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.66A 1jnoA-2jepA:
undetectable		 1jnoA-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.66A 1jnoB-2jepA:
undetectable		 1jnoB-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.77A 1jo3A-2jepA:
undetectable		 1jo3A-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.77A 1jo3B-2jepA:
undetectable		 1jo3B-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.79A 1jo4A-2jepA:
undetectable		 1jo4A-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.79A 1jo4B-2jepA:
undetectable		 1jo4B-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.73A 1magA-2jepA:
undetectable		 1magA-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.73A 1magB-2jepA:
undetectable		 1magB-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.66A 1ng8A-2jepA:
undetectable		 1ng8A-2jepA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.65A 1ng8B-2jepA:
undetectable		 1ng8B-2jepA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.86A 1nrmA-2jepA:
undetectable		 1nrmA-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.86A 1nrmB-2jepA:
undetectable		 1nrmB-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.72A 1nruA-2jepA:
undetectable		 1nruA-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 ALA A  54
VAL A  90
TRP A 108
 None
 0.72A 1nruB-2jepA:
undetectable		 1nruB-2jepA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		5 / 10 ASP A 362
ARG A 376
LEU A  74
ILE A 386
PHE A  83
 None
 1.11A 1q6iB-2jepA:
undetectable		 1q6iB-2jepA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		4 / 7 ASN A 129
ASN A  47
HIS A 264
VAL A 320
 None
 1.15A 1wu8A-2jepA:
undetectable
1wu8C-2jepA:
undetectable		 1wu8A-2jepA:
19.61
1wu8C-2jepA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 MET A 180
ASN A 146
GLN A 150
 None
 1.05A 1xoqB-2jepA:
undetectable		 1xoqB-2jepA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		5 / 12 ILE A 128
VAL A  90
TYR A  92
VAL A 116
LEU A  52
 None
 1.08A 1z9hD-2jepA:
undetectable		 1z9hD-2jepA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		6 / 12 ASN A 181
GLU A 182
HIS A 264
TYR A 266
GLU A 323
TRP A 361
 None
CA  A1398 ( 4.5A)
None
EDO  A1396 (-3.9A)
EDO  A1396 (-4.4A)
EDO  A1396 (-3.6A)
 0.84A 2v3dA-2jepA:
8.3		 2v3dA-2jepA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		4 / 7 GLU A 182
TYR A 188
PHE A 184
TYR A 135
 CA  A1398 ( 4.5A)
None
None
None
 1.30A 3ku9B-2jepA:
undetectable		 3ku9B-2jepA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 HIS A 131
SER A 179
GLU A 178
 None
 0.81A 3s8pA-2jepA:
undetectable		 3s8pA-2jepA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		4 / 5 ILE A 390
VAL A  78
LEU A  74
ASP A 362
 None
 1.02A 3wzdA-2jepA:
undetectable		 3wzdA-2jepA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		4 / 5 VAL A 320
LEU A 223
ILE A 127
ASN A  47
 None
 0.92A 4a9kB-2jepA:
undetectable		 4a9kB-2jepA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		4 / 8 ILE A 176
ILE A 127
VAL A 357
GLY A  45
 None
 0.79A 4ac9C-2jepA:
3.4		 4ac9C-2jepA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		4 / 8 ILE A 176
ILE A 127
VAL A 357
GLY A  45
 None
 0.77A 4acaC-2jepA:
3.6		 4acaC-2jepA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		4 / 8 ILE A 176
ILE A 127
VAL A 357
GLY A  45
 None
 0.77A 4acbC-2jepA:
3.5		 4acbC-2jepA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		5 / 11 LEU A 109
TYR A  92
VAL A  90
ILE A 128
LEU A 175
 None
 1.47A 4lhmA-2jepA:
undetectable		 4lhmA-2jepA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 PRO A  89
ASN A 181
HIS A 264
 None
 1.03A 4ma3H-2jepA:
undetectable
4ma3L-2jepA:
undetectable		 4ma3H-2jepA:
21.47
4ma3L-2jepA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_G_SPMG202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		5 / 9 ASN A 181
ARG A  87
ASN A 363
GLU A 323
GLU A  53
 None
None
None
EDO  A1396 (-4.4A)
None
 1.32A 4r87E-2jepA:
0.0
4r87G-2jepA:
0.0		 4r87E-2jepA:
22.41
4r87G-2jepA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 TYR A 266
SER A 326
TRP A 269
 EDO  A1396 (-3.9A)
None
None
 1.08A 5n8jB-2jepA:
undetectable		 5n8jB-2jepA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 TYR A 266
SER A 326
TRP A 269
 EDO  A1396 (-3.9A)
None
None
 1.03A 5n8jA-2jepA:
undetectable		 5n8jA-2jepA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		3 / 3 TYR A 266
SER A 326
TRP A 269
 EDO  A1396 (-3.9A)
None
None
 1.03A 5n8jD-2jepA:
undetectable		 5n8jD-2jepA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		4 / 6 GLU A 182
TYR A 135
GLY A 141
GLY A 140
 CA  A1398 ( 4.5A)
None
None
None
 0.95A 5x7pB-2jepA:
1.8		 5x7pB-2jepA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2jep XYLOGLUCANASE
(Paenibacillus
pabuli) 		5 / 12 PRO A 225
ILE A 261
MET A 260
GLY A 322
ALA A 263
 None
 1.06A 5zw4A-2jepA:
2.1		 5zw4A-2jepA:
18.69