SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jex'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA257_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		4 / 4 THR A 161
ALA A 148
GLN A 146
MET A 139
 None
 1.49A 1jgsA-2jexA:
0.0		 1jgsA-2jexA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		5 / 12 GLY A 151
ALA A 152
ASP A 153
VAL A 119
VAL A 117
 None
 0.81A 1k6cB-2jexA:
undetectable		 1k6cB-2jexA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		5 / 12 GLY A 151
ALA A 152
ASP A 153
VAL A 119
VAL A 117
 None
 0.85A 3el5B-2jexA:
undetectable		 3el5B-2jexA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		4 / 6 SER A 199
TYR A 186
VAL A 119
THR A 183
 None
 1.05A 3tneA-2jexA:
undetectable		 3tneA-2jexA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		3 / 3 GLU A 120
GLY A 123
SER A 187
 None
 0.70A 4b53B-2jexA:
undetectable		 4b53B-2jexA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		3 / 3 GLU A 176
ALA A 177
PHE A 180
 None
 0.48A 4v1fA-2jexA:
2.8		 4v1fA-2jexA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		3 / 3 GLU A 176
ALA A 177
PHE A 180
 None
 0.46A 4v1fC-2jexA:
2.8		 4v1fC-2jexA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5H_A_ACTA1229_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		4 / 4 VAL A 188
GLU A 120
THR A 128
GLU A 118
 None
 1.47A 5g5hA-2jexA:
undetectable		 5g5hA-2jexA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		4 / 6 GLU A 176
THR A 132
TYR A 131
PHE A 121
 None
 1.40A 5lrbA-2jexA:
undetectable		 5lrbA-2jexA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 2jex REGULATORY PROTEIN
E2
(Deltapapillomavi
rus
4) 		4 / 6 GLU A 176
THR A 132
TYR A 131
PHE A 180
 None
 1.00A 5lrbA-2jexA:
undetectable		 5lrbA-2jexA:
12.77