SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jf3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		4 / 6 TYR A 219
ILE A 261
PRO A 182
PHE A 249
 None
 1.34A 1oniA-2jf3A:
undetectable
1oniC-2jf3A:
undetectable		 1oniA-2jf3A:
19.40
1oniC-2jf3A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		6 / 12 GLY A  17
ALA A  18
ILE A  38
VAL A  50
ILE A  13
ILE A  20
 None
 1.16A 2rkgA-2jf3A:
undetectable		 2rkgA-2jf3A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 7 VAL A 177
ILE A 261
ALA A 187
VAL A 171
GLY A 176
 None
 1.36A 2xrzB-2jf3A:
undetectable		 2xrzB-2jf3A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		4 / 7 VAL A 147
LEU A 117
ASN A  90
ILE A 123
 None
 0.99A 3rfmA-2jf3A:
undetectable		 3rfmA-2jf3A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A 222
LEU A 260
PHE A 252
GLY A 166
 None
 0.85A 3sj1X-2jf3A:
undetectable		 3sj1X-2jf3A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 VAL A  50
ILE A  68
ILE A   2
HIS A  35
VAL A  84
 None
 1.34A 4a97B-2jf3A:
undetectable
4a97C-2jf3A:
undetectable		 4a97B-2jf3A:
19.51
4a97C-2jf3A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		4 / 7 ILE A 222
LEU A 260
PHE A 252
GLY A 166
 None
 1.00A 4hajA-2jf3A:
undetectable		 4hajA-2jf3A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 10 TYR A 223
VAL A 185
TYR A 219
VAL A 169
ILE A 165
 None
 1.36A 4jtqA-2jf3A:
undetectable		 4jtqA-2jf3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_B_FLPB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 9 TYR A 223
VAL A 185
TYR A 219
VAL A 169
ILE A 165
 None
 1.41A 4jtqB-2jf3A:
0.0		 4jtqB-2jf3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		4 / 4 ILE A 215
VAL A 169
VAL A 197
ARG A 216
 None
 1.00A 4m6tA-2jf3A:
undetectable		 4m6tA-2jf3A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ILE A  86
ILE A  68
THR A 109
ASN A  72
ILE A 123
 None
 1.17A 5lg3J-2jf3A:
undetectable		 5lg3J-2jf3A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA A 151
GLY A 166
GLY A 143
ALA A 124
VAL A 159
 None
None
UD1  A1263 ( 3.7A)
None
None
 0.92A 5w4zB-2jf3A:
undetectable		 5w4zB-2jf3A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 VAL A 171
GLY A 166
ALA A 248
ALA A 167
ASP A 149
 None
 1.25A 5x7fA-2jf3A:
undetectable		 5x7fA-2jf3A:
21.93