SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 2jg6 DNA-3-METHYLADENINE
GLYCOSIDASE
(Staphylococcus
aureus) 		5 / 12 GLY A 101
SER A  39
LEU A  35
ILE A 105
LEU A 116
 None
 0.95A 1lhuA-2jg6A:
undetectable		 1lhuA-2jg6A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 2jg6 DNA-3-METHYLADENINE
GLYCOSIDASE
(Staphylococcus
aureus) 		4 / 7 ILE A  85
HIS A  88
LYS A  91
ILE A  95
 None
 1.10A 3eteD-2jg6A:
undetectable
3eteF-2jg6A:
undetectable		 3eteD-2jg6A:
17.10
3eteF-2jg6A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 2jg6 DNA-3-METHYLADENINE
GLYCOSIDASE
(Staphylococcus
aureus) 		5 / 9 LEU A 166
SER A 164
PHE A 165
GLU A  38
LEU A 157
 None
 1.49A 6ftpA-2jg6A:
0.0
6ftpB-2jg6A:
undetectable		 6ftpA-2jg6A:
17.74
6ftpB-2jg6A:
12.78