SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jgn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EUP_A_ASDA452_1 (CYTOCHROME P450ERYF)	2jgn	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	4 / 8	PHE A 515 LEU A 431 GLU A 463 LEU A 434	None	0.88A	1eupA-2jgnA: undetectable	1eupA-2jgnA: 18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NP1_A_HSMA303_1 (NITROPHORIN 1)	2jgn	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	4 / 5	GLU A 561 LEU A 555 LEU A 558 LEU A 556	None	0.95A	1np1A-2jgnA: undetectable	1np1A-2jgnA: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JN3_A_JN3A131_2 (FATTY ACID-BINDING PROTEIN, LIVER)	2jgn	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	4 / 6	LEU A 456 ASN A 435 ILE A 513 PHE A 515	None	0.89A	2jn3A-2jgnA: undetectable	2jn3A-2jgnA: 21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1Z_A_MXMA807_1 (PROSTAGLANDIN G/H SYNTHASE 1)	2jgn	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	5 / 12	ILE A 493 VAL A 445 GLY A 452 ALA A 453 LEU A 460	None	0.89A	4o1zA-2jgnA: undetectable	4o1zA-2jgnA: 13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_B_ADNB502_2 (ADENOSYLHOMOCYSTEINA SE)	2jgn	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	4 / 6	GLU A 463 THR A 443 HIS A 511 ASN A 435	None	1.34A	4pfjB-2jgnA: undetectable	4pfjB-2jgnA: 19.68

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EUP_A_ASDA452_1","CYTOCHROME P450ERYF","2jgn","ATP-DEPENDENT RNA HELICASE DDX3X","Homo sapiens",4,"PHE A 515;LEU A 431;GLU A 463;LEU A 434","None","0.88A","1eupA-2jgnA:undetectable","1eupA-2jgnA:18.86"],["1NP1_A_HSMA303_1","NITROPHORIN 1","2jgn","ATP-DEPENDENT RNA HELICASE DDX3X","Homo sapiens",4,"GLU A 561;LEU A 555;LEU A 558;LEU A 556","None","0.95A","1np1A-2jgnA:undetectable","1np1A-2jgnA:22.11"],["2JN3_A_JN3A131_2","FATTY ACID-BINDING PROTEIN, LIVER","2jgn","ATP-DEPENDENT RNA HELICASE DDX3X","Homo sapiens",4,"LEU A 456;ASN A 435;ILE A 513;PHE A 515","None","0.89A","2jn3A-2jgnA:undetectable","2jn3A-2jgnA:21.51"],["4O1Z_A_MXMA807_1","PROSTAGLANDIN G\/H SYNTHASE 1","2jgn","ATP-DEPENDENT RNA HELICASE DDX3X","Homo sapiens",5,"ILE A 493;VAL A 445;GLY A 452;ALA A 453;LEU A 460","None","0.89A","4o1zA-2jgnA:undetectable","4o1zA-2jgnA:13.88"],["4PFJ_B_ADNB502_2","ADENOSYLHOMOCYSTEINASE","2jgn","ATP-DEPENDENT RNA HELICASE DDX3X","Homo sapiens",4,"GLU A 463;THR A 443;HIS A 511;ASN A 435","None","1.34A","4pfjB-2jgnA:undetectable","4pfjB-2jgnA:19.68"]]