SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jgq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 2jgq TRIOSEPHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		4 / 5 ASP A  42
SER A  11
ASN A   8
SER A  18
 None
 1.50A 1kiaB-2jgqA:
undetectable		 1kiaB-2jgqA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_D_VIAD901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 2jgq TRIOSEPHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		5 / 11 TYR A 194
HIS A 179
LEU A 140
ALA A 163
LEU A  87
 None
 1.19A 3jwqA-2jgqA:
undetectable
3jwqD-2jgqA:
undetectable		 3jwqA-2jgqA:
24.46
3jwqD-2jgqA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 2jgq TRIOSEPHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		4 / 8 GLY A 214
TYR A 194
ALA A 157
GLU A 159
 None
 0.89A 3u9hB-2jgqA:
undetectable		 3u9hB-2jgqA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2jgq TRIOSEPHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		5 / 9 ILE A 118
LEU A 140
LEU A 149
ILE A 185
PHE A 108
 None
 1.29A 4r38C-2jgqA:
undetectable		 4r38C-2jgqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2jgq TRIOSEPHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		5 / 8 ILE A 118
LEU A 140
LEU A 149
ILE A 185
PHE A 108
 None
 1.30A 4r38D-2jgqA:
undetectable		 4r38D-2jgqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2jgq TRIOSEPHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		5 / 12 ILE A 230
VAL A  37
VAL A  39
ILE A 206
ALA A 203
 None
 1.16A 5n0sB-2jgqA:
undetectable		 5n0sB-2jgqA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 2jgq TRIOSEPHOSPHATE
ISOMERASE
(Helicobacter
pylori) 		5 / 12 VAL A  39
PRO A 160
VAL A 212
PHE A 227
ILE A 206
 None
 1.48A 6becA-2jgqA:
undetectable
6becB-2jgqA:
undetectable
6becC-2jgqA:
undetectable		 6becA-2jgqA:
18.83
6becB-2jgqA:
18.83
6becC-2jgqA:
18.83