SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jgv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AO8_A_MTXA170_1
(DIHYDROFOLATE
REDUCTASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 LEU A 162
LEU A   7
PHE A 121
LEU A   3
THR A 168
 None
 1.07A 1ao8A-2jgvA:
undetectable		 1ao8A-2jgvA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ASP A  12
GLY A  36
GLY A  37
ASN A  41
ASP A 254
 None
 0.93A 1bx4A-2jgvA:
25.1		 1bx4A-2jgvA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ASP A  12
GLY A  36
GLY A  37
ASN A  41
CYH A  90
 None
 0.99A 1bx4A-2jgvA:
25.1		 1bx4A-2jgvA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DGM_A_ADNA375_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 9 ASP A  12
GLY A  37
ASN A  41
CYH A  90
ASP A 254
 None
 1.04A 1dgmA-2jgvA:
26.5		 1dgmA-2jgvA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ASP A  12
GLY A  36
GLY A  37
ASN A  41
ASP A 254
 None
 0.92A 1likA-2jgvA:
24.6		 1likA-2jgvA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ASP A  12
GLY A  36
GLY A  37
ASN A  41
CYH A  90
 None
 0.96A 1likA-2jgvA:
24.6		 1likA-2jgvA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		3 / 3 ILE A   2
ILE A 161
LEU A  71
 None
 0.47A 2prgA-2jgvA:
undetectable		 2prgA-2jgvA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 LEU A   7
PHE A  58
LEU A   5
LEU A 125
VAL A 128
 None
 1.30A 2qd4B-2jgvA:
2.6		 2qd4B-2jgvA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		3 / 3 LEU A 137
PRO A 138
LEU A 141
 None
 0.50A 2qd5B-2jgvA:
3.1		 2qd5B-2jgvA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		4 / 6 LEU A 173
ILE A 182
ILE A   2
LEU A   5
 None
 0.90A 2xkwB-2jgvA:
undetectable		 2xkwB-2jgvA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 SER A 134
ILE A 260
LEU A  46
VAL A  42
THR A 256
 None
 1.27A 3dcjA-2jgvA:
4.9
3dcjB-2jgvA:
5.5		 3dcjA-2jgvA:
20.41
3dcjB-2jgvA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A  57
ALA A  55
THR A  43
ILE A   2
ILE A 264
 None
 1.35A 3ld6A-2jgvA:
undetectable		 3ld6A-2jgvA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		6 / 11 VAL A 239
ALA A 230
ARG A 238
SER A 222
VAL A 181
ALA A 277
 None
 1.08A 3qxvC-2jgvA:
undetectable		 3qxvC-2jgvA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ALA A 230
ARG A 238
SER A 222
VAL A 181
ALA A 277
 None
 1.08A 3qxvE-2jgvA:
undetectable		 3qxvE-2jgvA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		4 / 6 LEU A   5
SER A  56
ALA A  79
LEU A   7
 None
 1.06A 3ravA-2jgvA:
undetectable		 3ravA-2jgvA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		4 / 6 LEU A   5
SER A  56
ALA A  79
LEU A   7
 None
 1.05A 3rd0A-2jgvA:
undetectable		 3rd0A-2jgvA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		6 / 9 ASN A  41
GLY A  37
GLY A  36
SER A 134
GLY A  39
ASP A 254
 None
 1.37A 3ztvA-2jgvA:
undetectable		 3ztvA-2jgvA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		4 / 7 GLY A  39
THR A   4
LEU A  71
PHE A  80
 None
 0.87A 4ejjD-2jgvA:
undetectable		 4ejjD-2jgvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		4 / 8 GLU A 108
ASN A   8
GLN A 105
GLY A 106
 None
 0.99A 4f93B-2jgvA:
undetectable		 4f93B-2jgvA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ASP A  12
GLY A  36
GLY A  37
ASN A  41
ASP A 254
 None
 0.87A 4n09B-2jgvA:
25.8		 4n09B-2jgvA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A  36
GLY A  37
ASN A  41
GLY A 251
ASP A 254
 None
 0.72A 4n09B-2jgvA:
25.8		 4n09B-2jgvA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ASP A  12
GLY A  36
GLY A  37
ASN A  41
ASP A 254
 None
 0.88A 4n09C-2jgvA:
25.8		 4n09C-2jgvA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A  36
GLY A  37
ASN A  41
GLY A 251
ASP A 254
 None
 0.73A 4n09C-2jgvA:
25.8		 4n09C-2jgvA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ASP A  12
GLY A  36
GLY A  37
ASN A  41
ASP A 254
 None
 0.86A 4n09D-2jgvA:
25.7		 4n09D-2jgvA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ASP A  12
GLY A  36
GLY A  37
ASN A  41
CYH A  90
 None
 0.99A 4n09D-2jgvA:
25.7		 4n09D-2jgvA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A  36
GLY A  37
ASN A  41
GLY A 251
ASP A 254
 None
 0.71A 4n09D-2jgvA:
25.7		 4n09D-2jgvA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A  36
THR A   6
LEU A   7
ASN A   8
ILE A 133
 None
 1.30A 4n48A-2jgvA:
3.7		 4n48A-2jgvA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		5 / 12 LEU A 169
LEU A 204
ILE A 219
VAL A 221
LEU A 197
 None
 1.01A 4y0pA-2jgvA:
undetectable		 4y0pA-2jgvA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2jgv TAGATOSE-6-PHOSPHATE
KINASE
(Staphylococcus
aureus) 		3 / 3 GLY A 106
THR A  87
ASN A   8
 None
 0.69A 5odiG-2jgvA:
5.4		 5odiG-2jgvA:
19.52