SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jh3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 8 ALA A 278
TRP A 279
PHE A 439
GLU A 376
None
1.06A 1dmiA-2jh3A:
undetectable
1dmiB-2jh3A:
undetectable
1dmiA-2jh3A:
22.74
1dmiB-2jh3A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 12 LEU A 362
ALA A 286
LEU A 282
ALA A 278
ILE A 374
None
1.06A 1fk6A-2jh3A:
undetectable
1fk6A-2jh3A:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
3 / 4 VAL A 454
TRP A 340
TRP A 346
None
None
SF4  A 650 (-4.6A)
1.43A 1gmkC-2jh3A:
undetectable
1gmkD-2jh3A:
undetectable
1gmkC-2jh3A:
7.37
1gmkD-2jh3A:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 12 LEU A   6
LEU A 258
ALA A 116
VAL A 255
TYR A 110
None
1.08A 1kt4A-2jh3A:
undetectable
1kt4A-2jh3A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 10 GLY A 119
VAL A 254
LEU A 114
LEU A  72
ALA A 123
None
1.41A 1pbcA-2jh3A:
undetectable
1pbcA-2jh3A:
25.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 10 LEU A  43
ALA A 276
ALA A  61
VAL A   5
LEU A  57
None
1.15A 1rlbE-2jh3A:
undetectable
1rlbE-2jh3A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 LEU A  43
ALA A 276
ALA A  61
VAL A   5
LEU A  57
None
1.01A 1rlbF-2jh3A:
undetectable
1rlbF-2jh3A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 8 THR A 437
GLY A 441
ARG A 288
ILE A 438
None
0.98A 1rxcE-2jh3A:
undetectable
1rxcE-2jh3A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 8 THR A 437
GLY A 441
ARG A 288
ILE A 438
None
0.97A 1rxcK-2jh3A:
undetectable
1rxcK-2jh3A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
3 / 3 ARG A 427
VAL A 373
THR A 345
None
0.86A 2nnkA-2jh3A:
undetectable
2nnkA-2jh3A:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 12 SER A  63
GLY A 105
GLY A 104
LEU A   1
ALA A  61
None
0.96A 3douA-2jh3A:
2.5
3douA-2jh3A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
3 / 3 ARG A 427
VAL A 373
THR A 345
None
0.87A 3k4vA-2jh3A:
undetectable
3k4vA-2jh3A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
3 / 3 ARG A 427
VAL A 373
THR A 345
None
0.84A 3nduD-2jh3A:
undetectable
3nduD-2jh3A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
3 / 3 GLU A 326
LEU A 364
LEU A 303
None
0.77A 3ohtA-2jh3A:
undetectable
3ohtA-2jh3A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 7 LEU A  57
VAL A  60
VAL A  67
ASP A  64
None
0.86A 3rgfA-2jh3A:
undetectable
3rgfA-2jh3A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 8 THR A 437
GLY A 441
ARG A 288
ILE A 438
None
0.95A 4e1vC-2jh3A:
undetectable
4e1vC-2jh3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 8 THR A 437
GLY A 441
ARG A 288
ILE A 438
None
0.93A 4e1vD-2jh3A:
undetectable
4e1vD-2jh3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 8 THR A 437
GLY A 441
ARG A 288
ILE A 438
None
0.96A 4e1vE-2jh3A:
undetectable
4e1vE-2jh3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 6 GLY A 243
ALA A  20
GLU A 247
GLN A 223
None
1.14A 4g0uA-2jh3A:
2.4
4g0uA-2jh3A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 GLY A 170
ARG A 163
ALA A 159
LEU A 162
ALA A 252
None
1.14A 4l6v1-2jh3A:
undetectable
4l6v6-2jh3A:
undetectable
4l6v1-2jh3A:
21.34
4l6v6-2jh3A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 PHE A 168
ARG A 163
ALA A 159
LEU A 162
ALA A 252
None
1.13A 4l6v1-2jh3A:
undetectable
4l6v6-2jh3A:
undetectable
4l6v1-2jh3A:
21.34
4l6v6-2jh3A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 8 PRO A  69
VAL A 108
TYR A 110
LEU A  53
None
0.98A 4pwdA-2jh3A:
undetectable
4pwdA-2jh3A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 SER A  73
GLU A  74
ARG A 112
PRO A  93
THR A  78
None
1.38A 4urnA-2jh3A:
undetectable
4urnA-2jh3A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 SER A  73
GLU A  74
ARG A 112
PRO A  93
THR A  78
None
1.38A 4urnB-2jh3A:
undetectable
4urnB-2jh3A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 SER A  73
GLU A  74
ARG A 112
PRO A  93
THR A  78
None
1.36A 4urnC-2jh3A:
undetectable
4urnC-2jh3A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 LEU A 146
LEU A 207
LEU A 222
ALA A 229
LEU A 226
None
0.97A 4wg0B-2jh3A:
undetectable
4wg0C-2jh3A:
undetectable
4wg0D-2jh3A:
undetectable
4wg0B-2jh3A:
2.49
4wg0C-2jh3A:
2.49
4wg0D-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 LEU A 297
GLU A 367
LEU A 366
GLU A 375
LEU A 282
None
1.08A 4wg0B-2jh3A:
undetectable
4wg0C-2jh3A:
undetectable
4wg0D-2jh3A:
undetectable
4wg0B-2jh3A:
2.49
4wg0C-2jh3A:
2.49
4wg0D-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 GLU A 367
LEU A 366
GLU A 375
ALA A 278
LEU A 282
None
1.16A 4wg0D-2jh3A:
undetectable
4wg0E-2jh3A:
undetectable
4wg0F-2jh3A:
undetectable
4wg0D-2jh3A:
2.49
4wg0E-2jh3A:
2.49
4wg0F-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 LEU A 146
LEU A 207
LEU A 222
ALA A 229
LEU A 226
None
0.98A 4wg0D-2jh3A:
undetectable
4wg0E-2jh3A:
undetectable
4wg0F-2jh3A:
undetectable
4wg0D-2jh3A:
2.49
4wg0E-2jh3A:
2.49
4wg0F-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 LEU A 297
GLU A 367
LEU A 366
GLU A 375
LEU A 282
None
1.08A 4wg0D-2jh3A:
undetectable
4wg0E-2jh3A:
undetectable
4wg0F-2jh3A:
undetectable
4wg0D-2jh3A:
2.49
4wg0E-2jh3A:
2.49
4wg0F-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 ALA A 229
LEU A 226
LEU A 222
LEU A 146
LEU A 207
None
0.99A 4wg0C-2jh3A:
undetectable
4wg0D-2jh3A:
undetectable
4wg0E-2jh3A:
undetectable
4wg0C-2jh3A:
2.49
4wg0D-2jh3A:
2.49
4wg0E-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 LEU A 297
GLU A 367
LEU A 366
GLU A 375
LEU A 282
None
1.12A 4wg0F-2jh3A:
undetectable
4wg0G-2jh3A:
undetectable
4wg0H-2jh3A:
undetectable
4wg0F-2jh3A:
2.49
4wg0G-2jh3A:
2.49
4wg0H-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 ALA A 229
LEU A 226
LEU A 222
LEU A 146
LEU A 207
None
0.98A 4wg0E-2jh3A:
undetectable
4wg0F-2jh3A:
undetectable
4wg0G-2jh3A:
undetectable
4wg0E-2jh3A:
2.49
4wg0F-2jh3A:
2.49
4wg0G-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 GLU A 375
LEU A 282
GLU A 367
LEU A 366
LEU A 297
None
1.09A 4wg0G-2jh3A:
undetectable
4wg0H-2jh3A:
undetectable
4wg0I-2jh3A:
undetectable
4wg0G-2jh3A:
2.49
4wg0H-2jh3A:
2.49
4wg0I-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 11 ALA A 229
LEU A 226
LEU A 222
LEU A 146
LEU A 207
None
0.97A 4wg0K-2jh3A:
undetectable
4wg0L-2jh3A:
undetectable
4wg0M-2jh3A:
undetectable
4wg0K-2jh3A:
2.49
4wg0L-2jh3A:
2.49
4wg0M-2jh3A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 10 GLY A  52
GLU A  50
GLN A  55
ALA A 449
ALA A 451
None
None
None
None
SF4  A 650 ( 4.5A)
1.32A 4wnuD-2jh3A:
undetectable
4wnuD-2jh3A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 7 PHE A 168
ARG A 163
ALA A 159
LEU A 162
None
1.10A 4xk8A-2jh3A:
undetectable
4xk8A-2jh3A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 12 GLY A 365
LEU A 364
VAL A  70
THR A 324
LEU A 328
None
1.20A 5hg0A-2jh3A:
undetectable
5hg0A-2jh3A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
3 / 3 LEU A 145
LEU A 144
TRP A 196
None
0.80A 5nwuA-2jh3A:
undetectable
5nwuA-2jh3A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 12 ALA A  27
VAL A 254
ALA A 123
LEU A  72
LEU A 114
None
0.87A 5x23A-2jh3A:
undetectable
5x23A-2jh3A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
3 / 3 LEU A 455
VAL A 412
ASP A 413
SF4  A 650 (-4.1A)
None
None
0.49A 5x23A-2jh3A:
undetectable
5x23A-2jh3A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
5 / 12 ALA A  27
VAL A 254
ALA A 123
LEU A  72
LEU A 114
None
0.93A 5xxiA-2jh3A:
undetectable
5xxiA-2jh3A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 8 LEU A  53
VAL A  56
VAL A 108
VAL A  65
None
1.05A 6cp4A-2jh3A:
undetectable
6cp4A-2jh3A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB604_0
(AMINE OXIDASE LKCE)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 4 HIS A 158
PRO A 118
ALA A 121
ARG A 165
None
1.22A 6f32B-2jh3A:
0.0
6f32B-2jh3A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans)
4 / 7 ARG A 263
LEU A   6
TYR A  39
VAL A  68
None
1.13A 6g2pA-2jh3A:
undetectable
6g2pA-2jh3A:
23.06