SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 11 CYH A 318
HIS A 307
LEU A 386
MET A 369
LEU A 336
 None
 1.25A 1ee2A-2jh9A:
4.2		 1ee2A-2jh9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 11 CYH A 318
HIS A 307
LEU A 386
MET A 369
LEU A 336
 None
 1.25A 1ee2B-2jh9A:
undetectable		 1ee2B-2jh9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		3 / 4 VAL A 512
TRP A 571
TRP A 578
 None
 1.35A 1gmkA-2jh9A:
undetectable
1gmkB-2jh9A:
undetectable		 1gmkA-2jh9A:
5.85
1gmkB-2jh9A:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		3 / 4 VAL A 512
TRP A 571
TRP A 578
 None
 1.09A 1gmkC-2jh9A:
undetectable
1gmkD-2jh9A:
undetectable		 1gmkC-2jh9A:
5.85
1gmkD-2jh9A:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 4 ASP A 408
HIS A 133
ARG A 406
GLU A 131
 None
 1.02A 1lqtA-2jh9A:
2.4		 1lqtA-2jh9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 6 ILE A 166
PRO A 158
PHE A 170
ARG A 378
 None
 1.50A 1oniA-2jh9A:
undetectable
1oniC-2jh9A:
undetectable		 1oniA-2jh9A:
12.85
1oniC-2jh9A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 5 PHE A 170
ARG A 378
ILE A 166
PRO A 158
 None
 1.30A 1oniG-2jh9A:
undetectable
1oniH-2jh9A:
undetectable		 1oniG-2jh9A:
12.85
1oniH-2jh9A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 6 ARG A 380
TYR A 446
ASP A 448
ASN A 414
 None
GUN  A1647 (-4.0A)
None
None
 0.93A 1rjdA-2jh9A:
6.6		 1rjdA-2jh9A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 6 ARG A 380
TYR A 446
ASP A 448
ASN A 414
 None
GUN  A1647 (-4.0A)
None
None
 0.91A 1rjdB-2jh9A:
6.7		 1rjdB-2jh9A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 6 ARG A 380
TYR A 446
ASP A 448
ASN A 414
 None
GUN  A1647 (-4.0A)
None
None
 0.89A 1rjdC-2jh9A:
6.4		 1rjdC-2jh9A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		6 / 12 LEU A 179
TYR A 195
ILE A 196
GLY A 197
VAL A 242
VAL A 266
 None
 0.57A 1vptA-2jh9A:
14.5		 1vptA-2jh9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 6 ARG A 629
SER A 454
GLY A 562
ARG A 440
 None
 1.20A 2f7fA-2jh9A:
undetectable		 2f7fA-2jh9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 8 ASN A  41
GLU A  32
VAL A   7
TYR A  44
 None
 1.17A 2fl5E-2jh9A:
undetectable
2fl5F-2jh9A:
undetectable		 2fl5E-2jh9A:
17.54
2fl5F-2jh9A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 5 LEU A 517
MET A 457
LEU A 568
HIS A 554
 None
 1.24A 2jfaA-2jh9A:
undetectable		 2jfaA-2jh9A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 8 LEU A  78
LEU A  28
PRO A 493
VAL A   7
 None
 0.89A 2po5A-2jh9A:
2.6		 2po5A-2jh9A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 8 LEU A  78
LEU A  28
PRO A 493
VAL A   7
 None
 0.85A 2po5B-2jh9A:
3.0		 2po5B-2jh9A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 6 ILE A 433
SER A 431
ARG A 406
ILE A 130
 None
 1.15A 2q72A-2jh9A:
undetectable		 2q72A-2jh9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 5 LEU A 517
MET A 457
LEU A 568
HIS A 554
 None
 1.27A 2qxsA-2jh9A:
undetectable		 2qxsA-2jh9A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 5 LEU A 517
MET A 457
LEU A 568
HIS A 554
 None
 1.28A 2qxsB-2jh9A:
undetectable		 2qxsB-2jh9A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 7 GLU A 192
ILE A 248
ALA A 356
ILE A 319
 None
 0.79A 2xkwA-2jh9A:
undetectable		 2xkwA-2jh9A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 12 LEU A 475
ILE A 521
PHE A  69
VAL A  48
PHE A  67
 None
 1.17A 2ygpA-2jh9A:
undetectable		 2ygpA-2jh9A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 7 ASP A 589
SER A 593
TRP A 578
ASP A 567
 None
 1.31A 3bc9A-2jh9A:
undetectable		 3bc9A-2jh9A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 12 TYR A 185
ILE A 305
ILE A 196
VAL A 193
GLY A 289
 None
 1.01A 3bwcA-2jh9A:
3.3		 3bwcA-2jh9A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 12 TYR A 185
ILE A 305
ILE A 196
VAL A 193
GLY A 289
 None
 0.99A 3bwcB-2jh9A:
7.7		 3bwcB-2jh9A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 10 GLU A 630
LEU A 568
LEU A 458
HIS A 554
LEU A 555
 None
 1.43A 3erdB-2jh9A:
undetectable		 3erdB-2jh9A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		3 / 3 GLU A  13
HIS A  73
THR A  11
 None
 0.77A 3hkuA-2jh9A:
undetectable		 3hkuA-2jh9A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 7 LEU A 619
LEU A 644
PHE A 569
TRP A 637
 None
 1.25A 3nk2X-2jh9A:
undetectable		 3nk2X-2jh9A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 12 LEU A 475
ASP A 469
GLY A 470
ALA A 120
LEU A 489
 None
 1.16A 3p5nA-2jh9A:
undetectable		 3p5nA-2jh9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 12 LEU A 475
ASP A 469
GLY A 470
ALA A 120
LEU A 489
 None
 1.15A 3p5nB-2jh9A:
undetectable		 3p5nB-2jh9A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 11 ILE A 196
GLY A 289
GLU A 290
GLY A 297
HIS A 194
 None
 1.03A 4e47A-2jh9A:
undetectable		 4e47A-2jh9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 11 ILE A 196
GLY A 289
GLU A 290
GLY A 297
HIS A 194
 None
 1.04A 4e47B-2jh9A:
undetectable		 4e47B-2jh9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 11 ILE A 196
GLY A 289
GLU A 290
GLY A 297
HIS A 194
 None
 1.02A 4e47C-2jh9A:
undetectable		 4e47C-2jh9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 11 ILE A 196
GLY A 289
GLU A 290
GLY A 297
HIS A 194
 None
 1.05A 4jdsB-2jh9A:
undetectable		 4jdsB-2jh9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 11 ILE A 196
GLY A 289
GLU A 290
GLY A 297
HIS A 194
 None
 1.03A 4jdsC-2jh9A:
undetectable		 4jdsC-2jh9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 12 ILE A 196
GLY A 289
GLU A 290
GLY A 297
HIS A 194
 None
 1.02A 4jlgA-2jh9A:
undetectable		 4jlgA-2jh9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 8 LEU A  37
VAL A   7
TYR A   9
LEU A  62
 None
 1.03A 4pwdA-2jh9A:
undetectable		 4pwdA-2jh9A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		3 / 3 ARG A 202
GLN A 206
GLU A 177
 None
 0.91A 4tvtA-2jh9A:
undetectable		 4tvtA-2jh9A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 9 GLY A 439
ILE A 424
MET A 428
LEU A 412
THR A 413
 None
 1.22A 4x3mB-2jh9A:
undetectable		 4x3mB-2jh9A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 5 LEU A 517
MET A 457
LEU A 568
HIS A 554
 None
 1.26A 4xi3B-2jh9A:
undetectable		 4xi3B-2jh9A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 11 ILE A 196
GLY A 289
GLU A 290
GLY A 297
HIS A 194
 None
 1.00A 5ayfA-2jh9A:
undetectable		 5ayfA-2jh9A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 12 GLY A 197
GLY A 199
THR A 203
ASP A 224
PRO A 225
 None
 0.78A 5bw4A-2jh9A:
5.5		 5bw4A-2jh9A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		4 / 5 LEU A 261
ARG A 350
PHE A 339
LEU A 342
 None
 1.48A 5m10A-2jh9A:
undetectable		 5m10A-2jh9A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 12 GLY A  64
ASN A  41
GLU A  40
LEU A  37
LEU A  34
 None
 1.30A 5nwvA-2jh9A:
undetectable		 5nwvA-2jh9A:
4.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		3 / 3 MET A 113
GLU A 105
ARG A 109
 None
 1.01A 5tjyA-2jh9A:
2.5		 5tjyA-2jh9A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		3 / 3 MET A 113
GLU A 105
ARG A 109
 None
 0.94A 5tjzA-2jh9A:
undetectable		 5tjzA-2jh9A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		3 / 3 TYR A 195
ASP A 224
ASP A 265
 None
 0.28A 5x6yA-2jh9A:
15.7		 5x6yA-2jh9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		5 / 12 LEU A 179
TYR A 195
GLY A 197
ASP A 224
PRO A 225
 None
 0.37A 5x6yC-2jh9A:
15.8		 5x6yC-2jh9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 2jh9 VP4 CORE PROTEIN
(Bluetongue
virus) 		3 / 3 TYR A 223
HIS A 251
MET A 252
 None
 1.06A 6af6A-2jh9A:
undetectable		 6af6A-2jh9A:
21.17