SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ji9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 ILE A 482
SER A 422
MET A 428
TRP A 285
TYR A 483
 TPW  A1554 (-4.1A)
None
TPW  A1554 (-4.0A)
None
TPW  A1554 (-4.8A)
 1.10A 1kiaA-2ji9A:
undetectable		 1kiaA-2ji9A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 ILE A 482
SER A 422
MET A 428
TRP A 285
TYR A 483
 TPW  A1554 (-4.1A)
None
TPW  A1554 (-4.0A)
None
TPW  A1554 (-4.8A)
 1.09A 1nbhA-2ji9A:
undetectable		 1nbhA-2ji9A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 ILE A 482
SER A 422
MET A 428
TRP A 285
TYR A 483
 TPW  A1554 (-4.1A)
None
TPW  A1554 (-4.0A)
None
TPW  A1554 (-4.8A)
 1.09A 1nbhC-2ji9A:
3.2		 1nbhC-2ji9A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 ILE A 482
SER A 422
MET A 428
TRP A 285
TYR A 483
 TPW  A1554 (-4.1A)
None
TPW  A1554 (-4.0A)
None
TPW  A1554 (-4.8A)
 1.09A 1nbhD-2ji9A:
3.2		 1nbhD-2ji9A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 ILE A 476
VAL A 474
SER A 422
GLY A 459
SER A 458
 None
 0.94A 1nbiA-2ji9A:
5.0		 1nbiA-2ji9A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 ILE A 476
VAL A 474
SER A 422
GLY A 459
SER A 458
 None
 0.94A 1nbiB-2ji9A:
5.0		 1nbiB-2ji9A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 ASP A 452
THR A 370
GLY A 373
SER A 372
ALA A 543
 MG  A1555 ( 2.9A)
None
None
None
None
 1.21A 1nw5A-2ji9A:
undetectable		 1nw5A-2ji9A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 SER A 136
ARG A 130
ASN A 127
GLN A 125
 None
 1.11A 1p6kB-2ji9A:
undetectable		 1p6kB-2ji9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 SER A 136
ARG A 130
GLN A 125
ASP A 167
 None
 1.30A 1rs6B-2ji9A:
undetectable		 1rs6B-2ji9A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 11 ASP A 421
GLY A 431
GLY A 433
TYR A 434
SER A 458
 None
 1.38A 1w76A-2ji9A:
undetectable		 1w76A-2ji9A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 4 GLY A  60
SER A  64
ILE A 430
HIS A  93
 None
 1.25A 1yajJ-2ji9A:
undetectable		 1yajJ-2ji9A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 SER A 136
ARG A 130
GLN A 125
ASP A 167
 None
 1.28A 1zzqB-2ji9A:
undetectable		 1zzqB-2ji9A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 SER A 136
ARG A 130
ASN A 127
GLN A 125
 None
 1.10A 1zzuB-2ji9A:
undetectable		 1zzuB-2ji9A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 LYS A 352
ASP A 412
ASP A 386
 None
 0.84A 2br4A-2ji9A:
3.6		 2br4A-2ji9A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		6 / 12 GLY A 221
ALA A 224
VAL A 330
ILE A 305
VAL A 237
ILE A 233
 ADP  A1556 (-3.3A)
None
None
None
None
None
 1.50A 2f8gB-2ji9A:
undetectable		 2f8gB-2ji9A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		6 / 12 LEU A 254
GLY A 221
ALA A 224
ILE A 305
VAL A 237
ILE A 233
 None
ADP  A1556 (-3.3A)
None
None
None
None
 1.43A 2o4lB-2ji9A:
undetectable		 2o4lB-2ji9A:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 7 ILE A 139
PRO A  35
ILE A  36
LEU A  39
 None
 0.82A 2q83A-2ji9A:
undetectable		 2q83A-2ji9A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 LEU A 396
SER A 380
GLY A 451
MET A 477
 None
None
TPW  A1554 (-3.4A)
None
 1.10A 2qd5A-2ji9A:
2.3		 2qd5A-2ji9A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 PRO A 100
GLY A  71
TYR A 226
 None
None
ADP  A1556 ( 4.8A)
 0.68A 2vouA-2ji9A:
undetectable		 2vouA-2ji9A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 PRO A 100
GLY A  71
TYR A 226
 None
None
ADP  A1556 ( 4.8A)
 0.65A 2vouB-2ji9A:
undetectable		 2vouB-2ji9A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 PRO A 100
GLY A  71
TYR A 226
 None
None
ADP  A1556 ( 4.8A)
 0.65A 2vouC-2ji9A:
undetectable		 2vouC-2ji9A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 VAL A 217
LEU A 253
GLY A 221
ALA A 250
 None
None
ADP  A1556 (-3.3A)
None
 0.90A 2xfsA-2ji9A:
undetectable		 2xfsA-2ji9A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 VAL A 217
LEU A 253
GLY A 221
ALA A 250
 None
None
ADP  A1556 (-3.3A)
None
 0.89A 2xh9A-2ji9A:
undetectable		 2xh9A-2ji9A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		6 / 12 LEU A 254
GLY A 221
ALA A 224
ILE A 305
VAL A 237
ILE A 233
 None
ADP  A1556 (-3.3A)
None
None
None
None
 1.38A 3bvbA-2ji9A:
undetectable		 3bvbA-2ji9A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 10 ILE A 210
ALA A 207
ALA A 206
LEU A 337
ALA A 336
 None
 1.03A 3falC-2ji9A:
undetectable		 3falC-2ji9A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 11 ALA A 152
LEU A 104
VAL A 166
ILE A 145
LEU A 172
 None
 1.21A 3fl9C-2ji9A:
undetectable		 3fl9C-2ji9A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 10 ILE A  69
ARG A 417
PRO A 392
GLY A 252
MET A 413
 None
 1.47A 3hcpB-2ji9A:
2.9		 3hcpB-2ji9A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 GLU A 346
GLY A 349
THR A 348
 None
 0.56A 3iazA-2ji9A:
0.0		 3iazA-2ji9A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 9 THR A  27
TYR A  29
PHE A  53
ALA A 439
ILE A  69
 None
 1.47A 3jusB-2ji9A:
undetectable		 3jusB-2ji9A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 10 PHE A 457
GLY A 459
VAL A 427
ILE A 476
GLY A 431
 TPW  A1554 (-4.3A)
None
TPW  A1554 ( 4.8A)
None
None
 1.30A 3km6A-2ji9A:
undetectable		 3km6A-2ji9A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 ASP A 167
SER A 107
ARG A 110
 None
 0.93A 3loqA-2ji9A:
undetectable		 3loqA-2ji9A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N0H_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 11 THR A 442
ILE A  69
LEU A 420
VAL A 446
THR A 464
 None
 1.08A 3n0hA-2ji9A:
undetectable		 3n0hA-2ji9A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		6 / 12 LEU A 254
GLY A 221
ALA A 224
ILE A 305
VAL A 237
ILE A 233
 None
ADP  A1556 (-3.3A)
None
None
None
None
 1.38A 3nu5A-2ji9A:
undetectable		 3nu5A-2ji9A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 GLY A 431
ILE A 447
VAL A 446
 None
 0.52A 3nv6A-2ji9A:
undetectable		 3nv6A-2ji9A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 5 CYH A 435
TYR A 468
PRO A 471
THR A 473
 None
 1.33A 3q07A-2ji9A:
undetectable		 3q07A-2ji9A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 5 CYH A 435
TYR A 468
PRO A 471
THR A 473
 None
 1.34A 3q07B-2ji9A:
undetectable		 3q07B-2ji9A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 LEU A 420
GLY A 433
GLY A 431
ILE A 465
PHE A  53
 None
 1.00A 4a6dA-2ji9A:
3.4		 4a6dA-2ji9A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 LEU A 420
GLY A 433
GLY A 431
ILE A 465
PHE A  53
 None
 1.00A 4a6eA-2ji9A:
3.3		 4a6eA-2ji9A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 LEU A 529
LEU A 525
ILE A 475
GLY A 382
VAL A 383
 None
 0.75A 4an2A-2ji9A:
undetectable		 4an2A-2ji9A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		6 / 12 ALA A 235
ILE A 218
ILE A 279
SER A 331
VAL A 330
ILE A 326
 None
None
None
None
None
ADP  A1556 (-4.0A)
 1.26A 4ax8A-2ji9A:
2.6		 4ax8A-2ji9A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		6 / 12 ALA A 235
ILE A 218
ILE A 279
SER A 331
VAL A 330
ILE A 326
 None
None
None
None
None
ADP  A1556 (-4.0A)
 1.22A 4azvA-2ji9A:
undetectable		 4azvA-2ji9A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		6 / 12 LEU A 254
GLY A 221
ALA A 224
ILE A 305
VAL A 237
ILE A 233
 None
ADP  A1556 (-3.3A)
None
None
None
None
 1.45A 4jecA-2ji9A:
undetectable		 4jecA-2ji9A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 ILE A  69
MET A 249
ARG A 419
 None
 0.93A 4lnwA-2ji9A:
undetectable		 4lnwA-2ji9A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 ILE A  69
MET A 249
ARG A 419
 None
 0.96A 4lnxA-2ji9A:
undetectable		 4lnxA-2ji9A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 VAL A 474
ALA A 448
VAL A 446
PHE A 455
GLY A 431
 None
 1.24A 4mm4B-2ji9A:
undetectable		 4mm4B-2ji9A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 4 ALA A  59
ALA A  62
ALA A  63
ALA A  66
 None
 0.11A 4oadA-2ji9A:
undetectable		 4oadA-2ji9A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 4 ALA A  59
ALA A  62
ALA A  63
ALA A  66
 None
 0.10A 4oaeA-2ji9A:
undetectable		 4oaeA-2ji9A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 LEU A 103
CYH A  76
ALA A  40
ILE A  36
GLY A  83
 None
 0.96A 4r3aB-2ji9A:
undetectable		 4r3aB-2ji9A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 ASP A 393
ARG A 417
PRO A 416
 None
 1.07A 4wanC-2ji9A:
undetectable		 4wanC-2ji9A:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 7 GLY A 431
VAL A 472
ILE A 447
VAL A 446
 None
 0.79A 5ik1A-2ji9A:
undetectable		 5ik1A-2ji9A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 6 ILE A 475
GLY A 459
MET A 432
ILE A 476
 None
 0.89A 5j4nB-2ji9A:
undetectable		 5j4nB-2ji9A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 LEU A 381
GLU A 450
LEU A 396
ILE A 447
 None
 0.88A 5mzjA-2ji9A:
undetectable		 5mzjA-2ji9A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 ILE A 210
ALA A 207
ALA A 206
LEU A 337
ALA A 336
 None
 0.99A 5uanA-2ji9A:
undetectable		 5uanA-2ji9A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 MET A 247
SER A 261
ILE A 218
TYR A 302
CYH A 273
 ADP  A1556 (-4.1A)
None
None
None
None
 1.22A 5vlmA-2ji9A:
undetectable		 5vlmA-2ji9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 ILE A 210
ALA A 207
ALA A 206
LEU A 337
ALA A 336
 None
 0.98A 5z12C-2ji9A:
undetectable		 5z12C-2ji9A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		3 / 3 VAL A 436
TYR A  51
GLU A 461
 None
 0.98A 5zmqD-2ji9A:
undetectable
5zmqE-2ji9A:
undetectable		 5zmqD-2ji9A:
16.19
5zmqE-2ji9A:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		5 / 12 VAL A 330
VAL A 237
GLY A 241
ALA A 343
VAL A 303
 None
 1.14A 6bqgA-2ji9A:
undetectable		 6bqgA-2ji9A:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 6 ILE A 545
MET A 477
ASN A 478
ASP A 452
 None
None
None
MG  A1555 ( 2.9A)
 1.06A 6dhbA-2ji9A:
undetectable		 6dhbA-2ji9A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 ILE A 139
ALA A 152
VAL A 153
ARG A 151
 None
 1.03A 6hu9a-2ji9A:
undetectable
6hu9e-2ji9A:
0.0		 6hu9a-2ji9A:
22.67
6hu9e-2ji9A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2ji9 OXALYL-COA
DECARBOXYLASE
(Oxalobacter
formigenes) 		4 / 8 GLY A 163
VAL A 153
GLY A  60
ALA A  66
 None
 0.61A 6hu9H-2ji9A:
undetectable
6hu9e-2ji9A:
undetectable		 6hu9H-2ji9A:
9.09
6hu9e-2ji9A:
12.59