SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		3 / 3 GLU A  26
GLU A  32
LEU A  54
 None
 0.74A 1v8bA-2jj7A:
undetectable		 1v8bA-2jj7A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		3 / 3 GLU A  26
GLU A  32
LEU A  54
 None
 0.78A 1v8bB-2jj7A:
undetectable		 1v8bB-2jj7A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		5 / 10 LEU A 133
PHE A 142
LEU A  87
ILE A 177
ALA A  82
 None
 1.11A 2bxeB-2jj7A:
3.2		 2bxeB-2jj7A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		4 / 5 ILE A 154
THR A  91
PHE A  71
TYR A  86
 None
 1.35A 3em0A-2jj7A:
undetectable		 3em0A-2jj7A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		3 / 3 GLN A 128
PHE A  71
TYR A  86
 None
 1.00A 3ucjB-2jj7A:
undetectable		 3ucjB-2jj7A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		3 / 3 GLN A 128
PHE A  71
TYR A  86
 None
 0.97A 3ucjA-2jj7A:
undetectable		 3ucjA-2jj7A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		5 / 11 ALA A 179
SER A 178
ILE A 154
SER A 156
HIS A 149
 None
 1.37A 4bb2A-2jj7A:
undetectable
4bb2B-2jj7A:
undetectable		 4bb2A-2jj7A:
17.95
4bb2B-2jj7A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		4 / 5 ILE A 108
PHE A  20
SER A 156
HIS A 152
 None
 1.33A 4rzvB-2jj7A:
undetectable		 4rzvB-2jj7A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		4 / 7 ILE A 147
ILE A 132
THR A 155
ILE A 154
 None
 0.81A 5fukA-2jj7A:
undetectable
5fukB-2jj7A:
undetectable		 5fukA-2jj7A:
23.75
5fukB-2jj7A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 2jj7 HEMOLYSIN II
REGULATORY PROTEIN
(Bacillus
cereus) 		5 / 10 LEU A  13
ALA A  16
LEU A  54
ILE A 118
LEU A 103
 None
 1.42A 6cbzB-2jj7A:
undetectable		 6cbzB-2jj7A:
15.85