SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jjm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 6 PHE A 220
ILE A 202
LYS A 199
ALA A 229
 None
 1.18A 1hk2A-2jjmA:
undetectable		 1hk2A-2jjmA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 11 GLN A 214
ILE A 243
LEU A 246
THR A 324
LEU A 278
 None
 1.06A 1jg3A-2jjmA:
undetectable		 1jg3A-2jjmA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 11 GLN A 214
ILE A 243
LEU A 246
THR A 324
LEU A 278
 None
 1.05A 1jg3B-2jjmA:
4.9		 1jg3B-2jjmA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 11 ILE A 115
HIS A  98
GLY A   6
LEU A  23
HIS A  93
 None
 1.42A 1kyvA-2jjmA:
2.3
1kyvB-2jjmA:
2.3		 1kyvA-2jjmA:
20.05
1kyvB-2jjmA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 11 GLY A   6
LEU A  23
HIS A  93
ILE A 115
HIS A  98
 None
 1.39A 2a58A-2jjmA:
2.2
2a58E-2jjmA:
2.2		 2a58A-2jjmA:
20.05
2a58E-2jjmA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 11 ILE A 115
HIS A  98
GLY A   6
LEU A  23
HIS A  93
 None
 1.38A 2a58C-2jjmA:
2.2
2a58D-2jjmA:
2.4		 2a58C-2jjmA:
20.05
2a58D-2jjmA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 10 LEU A 335
LEU A 201
LEU A 276
ILE A 299
ALA A 328
 None
 0.98A 2bxeB-2jjmA:
undetectable		 2bxeB-2jjmA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 LEU A 289
LEU A 288
ARG A 302
TYR A 172
 None
 1.17A 2hc4A-2jjmA:
undetectable		 2hc4A-2jjmA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUB_A_2TNA134_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 4 LEU A  87
ILE A 109
HIS A  55
LYS A   4
 None
 1.50A 2oubA-2jjmA:
0.0		 2oubA-2jjmA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		3 / 3 HIS A  93
GLY A  24
ILE A   7
 None
 0.60A 4k50A-2jjmA:
undetectable		 4k50A-2jjmA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		3 / 3 HIS A  93
GLY A  24
ILE A   7
 None
 0.61A 4k50I-2jjmA:
undetectable		 4k50I-2jjmA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 TYR A 180
VAL A  19
GLY A  20
CYH A   9
SER A  16
 None
 1.26A 4ot2A-2jjmA:
undetectable		 4ot2A-2jjmA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 9 LEU A  90
LEU A  74
ILE A  37
SER A  76
ALA A  79
 None
 1.36A 4z69A-2jjmA:
0.0		 4z69A-2jjmA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 4 LEU A  87
ILE A 113
GLY A   6
ILE A 115
 None
 0.90A 5dzk3-2jjmA:
undetectable
5dzkm-2jjmA:
3.3		 5dzk3-2jjmA:
0.71
5dzkm-2jjmA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 5 ILE A 113
GLY A   6
ILE A 115
LEU A  87
 None
 0.87A 5dzkB-2jjmA:
4.4
5dzkI-2jjmA:
3.3
5dzkW-2jjmA:
undetectable		 5dzkB-2jjmA:
20.55
5dzkI-2jjmA:
19.90
5dzkW-2jjmA:
0.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 4 ILE A 113
GLY A   6
ILE A 115
LEU A  87
 None
 0.87A 5dzkl-2jjmA:
3.2
5dzkz-2jjmA:
undetectable		 5dzkl-2jjmA:
19.90
5dzkz-2jjmA:
0.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 VAL A 287
GLU A 282
LEU A 231
GLY A 300
LEU A 278
 None
 1.13A 5ogcB-2jjmA:
4.7		 5ogcB-2jjmA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A 289
ILE A 202
LEU A 269
HIS A 203
LEU A 277
 None
 1.25A 5toaB-2jjmA:
undetectable		 5toaB-2jjmA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 ILE A 306
LEU A 288
MET A 292
LEU A 289
 None
 0.99A 5u4sA-2jjmA:
8.9		 5u4sA-2jjmA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		6 / 10 GLY A  15
HIS A 120
VAL A 150
ASN A 173
GLU A 282
GLY A 285
 None
 0.64A 5vncC-2jjmA:
25.3		 5vncC-2jjmA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		6 / 10 GLY A  15
HIS A 120
VAL A 150
ASN A 173
LYS A 211
GLU A 282
 None
 0.79A 5vncC-2jjmA:
25.3		 5vncC-2jjmA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 ALA A  73
LYS A  77
GLU A  80
LEU A 104
 None
 1.07A 6ci6A-2jjmA:
undetectable		 6ci6A-2jjmA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		6 / 12 GLY A  14
GLY A  15
ASP A 123
VAL A 150
ASN A 173
GLY A 285
 None
 0.91A 6gneA-2jjmA:
29.8		 6gneA-2jjmA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		6 / 12 GLY A  14
GLY A  15
VAL A  19
VAL A 150
ASN A 173
GLY A 285
 None
 0.67A 6gneA-2jjmA:
29.8		 6gneA-2jjmA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		6 / 12 GLY A  14
GLY A  15
ASP A 123
VAL A 150
ASN A 173
GLY A 285
 None
 0.92A 6gneB-2jjmA:
29.7		 6gneB-2jjmA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 2jjm GLYCOSYL
TRANSFERASE, GROUP 1
FAMILY PROTEIN
(Bacillus
anthracis) 		6 / 12 GLY A  14
GLY A  15
VAL A  19
VAL A 150
ASN A 173
GLY A 285
 None
 0.66A 6gneB-2jjmA:
29.7		 6gneB-2jjmA:
25.86