SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jjx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 GLY A  51
GLY A  13
ILE A  55
GLY A 131
THR A 141
 None
 1.16A 1jg2A-2jjxA:
4.5		 1jg2A-2jjxA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		4 / 4 GLY A  88
SER A  92
VAL A  98
LEU A  86
 None
 1.15A 1yajB-2jjxA:
undetectable		 1yajB-2jjxA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		4 / 8 LEU A  86
ILE A  36
ILE A 129
ILE A 127
 None
 0.84A 2bu8A-2jjxA:
undetectable		 2bu8A-2jjxA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 ILE A  32
ILE A  36
LEU A  86
VAL A  46
VAL A  98
 None
 0.92A 2nnhA-2jjxA:
undetectable		 2nnhA-2jjxA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 LEU A   8
ASP A 142
GLY A 133
GLY A 132
THR A  79
 None
 1.21A 2uvnA-2jjxA:
undetectable		 2uvnA-2jjxA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 LEU A   8
ASP A 142
MET A 152
GLY A 133
GLY A 132
 None
 1.20A 2uvnA-2jjxA:
undetectable		 2uvnA-2jjxA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		4 / 7 ASN A 134
ALA A 200
ALA A 201
GLN A 147
 None
 0.85A 3a2qA-2jjxA:
undetectable		 3a2qA-2jjxA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		4 / 6 TYR A 143
ALA A 201
LEU A 204
ALA A 149
 None
 0.90A 3b6hB-2jjxA:
undetectable		 3b6hB-2jjxA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 10 ILE A 129
ILE A 127
VAL A  40
VAL A  89
LEU A  11
 None
 1.17A 3em0A-2jjxA:
undetectable		 3em0A-2jjxA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		3 / 3 ARG A  28
ILE A  50
THR A 140
 None
 0.64A 3ia4D-2jjxA:
2.4		 3ia4D-2jjxA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		6 / 12 LEU A  16
VAL A  89
GLY A  88
ILE A 127
LEU A  11
ILE A   9
 None
 1.20A 3ijdA-2jjxA:
undetectable		 3ijdA-2jjxA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 LEU A  16
VAL A  89
GLY A  88
ILE A 127
ILE A   9
 None
 1.05A 3ijdB-2jjxA:
undetectable		 3ijdB-2jjxA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		4 / 8 ILE A   9
ILE A 129
LEU A  86
ILE A  50
 None
 0.96A 4dtaB-2jjxA:
undetectable		 4dtaB-2jjxA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 ILE A  50
GLY A  52
GLY A  51
SER A  83
ILE A  80
 None
 1.02A 4kahB-2jjxA:
undetectable		 4kahB-2jjxA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 ILE A  50
GLY A  52
GLY A  51
SER A  83
ILE A  80
 None
 1.00A 4kalA-2jjxA:
undetectable		 4kalA-2jjxA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 ILE A  50
GLY A  52
GLY A  51
SER A  83
ILE A  80
 None
 1.02A 4kalB-2jjxA:
undetectable		 4kalB-2jjxA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 ILE A  50
GLY A  52
GLY A  51
SER A  83
ILE A  80
 None
 1.01A 4kbeB-2jjxA:
undetectable		 4kbeB-2jjxA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		4 / 7 LEU A   8
VAL A 146
PRO A 144
TYR A 113
 None
 1.01A 4lb2A-2jjxA:
undetectable		 4lb2A-2jjxA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 ILE A  50
GLY A  52
GLY A  51
SER A  83
ILE A  80
 None
 1.02A 4lcaA-2jjxA:
undetectable		 4lcaA-2jjxA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		6 / 10 ALA A 149
LEU A 158
LEU A 210
ALA A 156
LEU A 204
ALA A 205
 None
 1.45A 4zbrA-2jjxA:
undetectable		 4zbrA-2jjxA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		3 / 3 SER A 145
LEU A 122
MET A 152
 None
 0.81A 5ikrB-2jjxA:
undetectable		 5ikrB-2jjxA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 2jjx URIDYLATE KINASE
(Bacillus
anthracis) 		5 / 12 GLY A  52
GLY A  78
ASN A  54
SER A  83
THR A 141
 None
 1.15A 5yf0A-2jjxA:
3.5		 5yf0A-2jjxA:
19.45