SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jk7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 2jk7 BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 5 ALA A 321
GLY A 305
CYH A 303
LYS A 250
 None
None
ZN  A1347 (-2.2A)
None
 1.19A 2ylgA-2jk7A:
undetectable		 2ylgA-2jk7A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2jk7 BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 7 TRP A 310
TYR A 329
CYH A 327
CYH A 303
 BI6  A1346 (-3.7A)
None
ZN  A1347 (-2.3A)
ZN  A1347 (-2.2A)
 1.14A 3peoF-2jk7A:
0.0		 3peoF-2jk7A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 2jk7 BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 5 ALA A 321
GLY A 305
CYH A 303
LYS A 250
 None
None
ZN  A1347 (-2.2A)
None
 1.24A 5jliA-2jk7A:
undetectable		 5jliA-2jk7A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 2jk7 BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 TYR A 329
HIS A 302
PHE A 301
 None
 0.92A 6esmA-2jk7A:
undetectable		 6esmA-2jk7A:
20.21