SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jli'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E00_A_9CRA7223_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2jli	YOP PROTEINS TRANSLOCATION PROTEIN (Yersinia pestis)	5 / 12	ILE A 269 GLN A 330 ALA A 315 VAL A 295 ILE A 306	None	1.08A	3e00A-2jliA: undetectable	3e00A-2jliA: 15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_C_SAMC301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	2jli	YOP PROTEINS TRANSLOCATION PROTEIN (Yersinia pestis)	5 / 12	PRO A 264 SER A 257 ILE A 326 ARG A 314 LEU A 316	None	1.27A	3iv6C-2jliA: undetectable	3iv6C-2jliA: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WXO_A_NIZA804_1 (CATALASE-PEROXIDASE)	2jli	YOP PROTEINS TRANSLOCATION PROTEIN (Yersinia pestis)	3 / 3	ASN A 249 GLU A 252 ARG A 256	None	1.05A	3wxoA-2jliA: undetectable	3wxoA-2jliA: 10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z7F_A_FOLA201_0 (FOLATE ECF TRANSPORTER)	2jli	YOP PROTEINS TRANSLOCATION PROTEIN (Yersinia pestis)	5 / 12	SER A 257 ALA A 320 TYR A 317 THR A 288 ASN A 249	None	1.31A	4z7fA-2jliA: undetectable	4z7fA-2jliA: 18.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3E00_A_9CRA7223_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2jli","YOP PROTEINS TRANSLOCATION PROTEIN","Yersinia pestis",5,"ILE A 269;GLN A 330;ALA A 315;VAL A 295;ILE A 306","None","1.08A","3e00A-2jliA:undetectable","3e00A-2jliA:15.48"],["3IV6_C_SAMC301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","2jli","YOP PROTEINS TRANSLOCATION PROTEIN","Yersinia pestis",5,"PRO A 264;SER A 257;ILE A 326;ARG A 314;LEU A 316","None","1.27A","3iv6C-2jliA:undetectable","3iv6C-2jliA:18.63"],["3WXO_A_NIZA804_1","CATALASE-PEROXIDASE","2jli","YOP PROTEINS TRANSLOCATION PROTEIN","Yersinia pestis",3,"ASN A 249;GLU A 252;ARG A 256","None","1.05A","3wxoA-2jliA:undetectable","3wxoA-2jliA:10.77"],["4Z7F_A_FOLA201_0","FOLATE ECF TRANSPORTER","2jli","YOP PROTEINS TRANSLOCATION PROTEIN","Yersinia pestis",5,"SER A 257;ALA A 320;TYR A 317;THR A 288;ASN A 249","None","1.31A","4z7fA-2jliA:undetectable","4z7fA-2jliA:18.69"]]