SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jlm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE
(Acinetobacter
baylyi) 		4 / 5 LEU A  73
ILE A  27
LEU A  28
ARG A  44
 None
None
ACT  A1183 ( 4.5A)
ACT  A1183 ( 3.8A)
 0.93A 2byoA-2jlmA:
undetectable		 2byoA-2jlmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE
(Acinetobacter
baylyi) 		3 / 3 HIS A  94
MET A 112
MET A 127
 None
 1.24A 2vj1A-2jlmA:
undetectable		 2vj1A-2jlmA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE
(Acinetobacter
baylyi) 		4 / 5 ILE A 139
GLN A 143
ILE A 148
TYR A 169
 None
 1.25A 4a99D-2jlmA:
undetectable		 4a99D-2jlmA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE
(Acinetobacter
baylyi) 		4 / 6 ILE A  27
ILE A  63
SER A  78
LEU A 111
 None
 0.87A 4m51A-2jlmA:
undetectable		 4m51A-2jlmA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE
(Acinetobacter
baylyi) 		5 / 12 ALA A  37
ARG A 103
ASN A 135
ALA A 137
LEU A 141
 None
 0.80A 4oaeA-2jlmA:
18.2		 4oaeA-2jlmA:
26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE
(Acinetobacter
baylyi) 		4 / 7 HIS A  94
HIS A 142
LEU A 145
SER A 138
 None
 1.03A 5m8rA-2jlmA:
undetectable		 5m8rA-2jlmA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE
(Acinetobacter
baylyi) 		4 / 8 HIS A  94
HIS A 142
LEU A 145
SER A 138
 None
 1.03A 5m8rB-2jlmA:
undetectable		 5m8rB-2jlmA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE
(Acinetobacter
baylyi) 		4 / 8 HIS A  94
HIS A 142
LEU A 145
SER A 138
 None
 1.01A 5m8rD-2jlmA:
undetectable		 5m8rD-2jlmA:
16.59