SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jm1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2jm1 TRANSCRIPTIONAL
REGULATOR ATRX
(Homo
sapiens) 		4 / 5 VAL A 178
CYH A 171
ALA A 173
CYH A 174
 None
ZN  A   1 (-2.3A)
ZN  A   1 ( 4.5A)
ZN  A   1 (-2.3A)
 0.96A 1mz9D-2jm1A:
undetectable		 1mz9D-2jm1A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2jm1 TRANSCRIPTIONAL
REGULATOR ATRX
(Homo
sapiens) 		5 / 12 PHE A 239
CYH A 243
HIS A 189
LEU A 192
LEU A 276
 None
ZN  A   2 (-2.3A)
None
None
None
 1.44A 3adsA-2jm1A:
undetectable		 3adsA-2jm1A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 2jm1 TRANSCRIPTIONAL
REGULATOR ATRX
(Homo
sapiens) 		3 / 3 TYR A 187
LYS A 202
LYS A 198
 None
 0.98A 5dbyA-2jm1A:
undetectable		 5dbyA-2jm1A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 2jm1 TRANSCRIPTIONAL
REGULATOR ATRX
(Homo
sapiens) 		4 / 7 CYH A 174
ILE A 196
ALA A 224
HIS A 189
 ZN  A   1 (-2.3A)
None
None
None
 0.90A 5hrqE-2jm1A:
undetectable
5hrqF-2jm1A:
undetectable
5hrqJ-2jm1A:
undetectable		 5hrqE-2jm1A:
13.91
5hrqF-2jm1A:
9.22
5hrqJ-2jm1A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 2jm1 TRANSCRIPTIONAL
REGULATOR ATRX
(Homo
sapiens) 		3 / 3 GLY A 227
GLN A 219
LYS A 242
 None
 0.98A 5imsB-2jm1A:
undetectable		 5imsB-2jm1A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 2jm1 TRANSCRIPTIONAL
REGULATOR ATRX
(Homo
sapiens) 		4 / 6 ASN A 237
CYH A 232
PHE A 239
TYR A 204
 None
ZN  A   3 (-2.3A)
None
None
 1.30A 6a7pB-2jm1A:
undetectable		 6a7pB-2jm1A:
13.22