SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jml'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_A_NCAA1252_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	2jml	DNA BINDING DOMAIN/TRANSCRIPTION AL REGULATOR (Myxococcus xanthus)	4 / 7	SER A 63 ARG A 52 GLN A 70 GLU A 66	None	1.34A	2c8aA-2jmlA: undetectable	2c8aA-2jmlA: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JB7_B_ACTB1169_0 (HYPOTHETICAL PROTEIN PAE2307)	2jml	DNA BINDING DOMAIN/TRANSCRIPTION AL REGULATOR (Myxococcus xanthus)	3 / 3	ARG A 51 ARG A 55 ARG A 52	None	1.20A	2jb7A-2jmlA: undetectable 2jb7B-2jmlA: undetectable 2jb7C-2jmlA: undetectable	2jb7A-2jmlA: 20.67 2jb7B-2jmlA: 20.67 2jb7C-2jmlA: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TJY_A_BEZA304_0 (4-HYDROXY-TETRAHYDRO DIPICOLINATE REDUCTASE)	2jml	DNA BINDING DOMAIN/TRANSCRIPTION AL REGULATOR (Myxococcus xanthus)	3 / 3	MET A 11 GLU A 48 ARG A 51	None	1.07A	5tjyA-2jmlA: undetectable	5tjyA-2jmlA: 15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TJZ_A_BEZA302_0 (4-HYDROXY-TETRAHYDRO DIPICOLINATE REDUCTASE)	2jml	DNA BINDING DOMAIN/TRANSCRIPTION AL REGULATOR (Myxococcus xanthus)	3 / 3	MET A 11 GLU A 48 ARG A 51	None	1.09A	5tjzA-2jmlA: undetectable	5tjzA-2jmlA: 15.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2C8A_A_NCAA1252_0","MONO-ADP-RIBOSYLTRANSFERASE C3","2jml","DNA BINDING DOMAIN\/TRANSCRIPTIONAL REGULATOR","Myxococcus xanthus",4,"SER A  63;ARG A  52;GLN A  70;GLU A  66","None","1.34A","2c8aA-2jmlA:undetectable","2c8aA-2jmlA:17.06"],["2JB7_B_ACTB1169_0","HYPOTHETICAL PROTEIN PAE2307","2jml","DNA BINDING DOMAIN\/TRANSCRIPTIONAL REGULATOR","Myxococcus xanthus",3,"ARG A  51;ARG A  55;ARG A  52","None","1.20A","2jb7A-2jmlA:undetectable;2jb7B-2jmlA:undetectable;2jb7C-2jmlA:undetectable","2jb7A-2jmlA:20.67;2jb7B-2jmlA:20.67;2jb7C-2jmlA:20.67"],["5TJY_A_BEZA304_0","4-HYDROXY-TETRAHYDRODIPICOLINATE REDUCTASE","2jml","DNA BINDING DOMAIN\/TRANSCRIPTIONAL REGULATOR","Myxococcus xanthus",3,"MET A  11;GLU A  48;ARG A  51","None","1.07A","5tjyA-2jmlA:undetectable","5tjyA-2jmlA:15.92"],["5TJZ_A_BEZA302_0","4-HYDROXY-TETRAHYDRODIPICOLINATE REDUCTASE","2jml","DNA BINDING DOMAIN\/TRANSCRIPTIONAL REGULATOR","Myxococcus xanthus",3,"MET A  11;GLU A  48;ARG A  51","None","1.09A","5tjzA-2jmlA:undetectable","5tjzA-2jmlA:15.92"]]