SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jmm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X8O_A_OINA1314_1 (CHOLINE-BINDING PROTEIN F)	2jmm	OUTER MEMBRANE PROTEIN A (Escherichia coli)	4 / 5	LYS A 62 ARG A 78 TYR A 76 GLU A 129	None	1.25A	2x8oA-2jmmA: 0.0	2x8oA-2jmmA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QOW_A_SAMA417_1 (HISTONE-LYSINE N-METHYLTRANSFERASE)	2jmm	OUTER MEMBRANE PROTEIN A (Escherichia coli)	3 / 3	THR A 121 ASP A 72 GLU A 113	None	0.85A	3qowA-2jmmA: undetectable	3qowA-2jmmA: 18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_B_PAUB601_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	2jmm	OUTER MEMBRANE PROTEIN A (Escherichia coli)	4 / 7	TYR A 76 GLU A 129 GLY A 43 GLY A 10	None	0.89A	5e26A-2jmmA: undetectable 5e26B-2jmmA: undetectable	5e26A-2jmmA: 18.33 5e26B-2jmmA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E26_C_PAUC602_0 (PANTOTHENATE KINASE 2, MITOCHONDRIAL)	2jmm	OUTER MEMBRANE PROTEIN A (Escherichia coli)	4 / 7	GLU A 129 GLY A 43 GLY A 10 TYR A 76	None	0.82A	5e26C-2jmmA: undetectable 5e26D-2jmmA: undetectable	5e26C-2jmmA: 18.33 5e26D-2jmmA: 18.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2X8O_A_OINA1314_1","CHOLINE-BINDING PROTEIN F","2jmm","OUTER MEMBRANE PROTEIN A","Escherichia coli",4,"LYS A  62;ARG A  78;TYR A  76;GLU A 129","None","1.25A","2x8oA-2jmmA:0.0","2x8oA-2jmmA:19.75"],["3QOW_A_SAMA417_1","HISTONE-LYSINE N-METHYLTRANSFERASE","2jmm","OUTER MEMBRANE PROTEIN A","Escherichia coli",3,"THR A 121;ASP A  72;GLU A 113","None","0.85A","3qowA-2jmmA:undetectable","3qowA-2jmmA:18.68"],["5E26_B_PAUB601_0","PANTOTHENATE KINASE 2, MITOCHONDRIAL","2jmm","OUTER MEMBRANE PROTEIN A","Escherichia coli",4,"TYR A  76;GLU A 129;GLY A  43;GLY A  10","None","0.89A","5e26A-2jmmA:undetectable;5e26B-2jmmA:undetectable","5e26A-2jmmA:18.33;5e26B-2jmmA:18.33"],["5E26_C_PAUC602_0","PANTOTHENATE KINASE 2, MITOCHONDRIAL","2jmm","OUTER MEMBRANE PROTEIN A","Escherichia coli",4,"GLU A 129;GLY A  43;GLY A  10;TYR A  76","None","0.82A","5e26C-2jmmA:undetectable;5e26D-2jmmA:undetectable","5e26C-2jmmA:18.33;5e26D-2jmmA:18.33"]]