SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jmz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SBR_B_VIBB504_1 (YKOF)	2jmz	HYPOTHETICAL PROTEIN MJ0781 (Methanocaldococc us jannaschii)	4 / 6	PRO A 104 HIS A 103 LEU A 155 SER A 61	None	1.20A	1sbrA-2jmzA: undetectable 1sbrB-2jmzA: undetectable	1sbrA-2jmzA: 18.40 1sbrB-2jmzA: 18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VRJ_A_1KXA301_1 (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN 10-MER PEPTIDE)	2jmz	HYPOTHETICAL PROTEIN MJ0781 (Methanocaldococc us jannaschii)	5 / 12	ILE A 52 VAL A 77 TYR A 153 ILE A 59 ILE A 57	None	1.21A	3vrjA-2jmzA: undetectable 3vrjC-2jmzA: undetectable	3vrjA-2jmzA: 20.15 3vrjC-2jmzA: 12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSW_A_P06A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2jmz	HYPOTHETICAL PROTEIN MJ0781 (Methanocaldococc us jannaschii)	3 / 3	PHE A 28 ILE A 15 ASP A 12	None	0.73A	5cswA-2jmzA: undetectable	5cswA-2jmzA: 19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DQY_A_BEZA401_0 (THIOREDOXIN)	2jmz	HYPOTHETICAL PROTEIN MJ0781 (Methanocaldococc us jannaschii)	4 / 8	ILE A 50 PHE A 32 VAL A 77 GLU A 55	None	1.08A	5dqyA-2jmzA: undetectable	5dqyA-2jmzA: 17.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1SBR_B_VIBB504_1","YKOF;YKOF","2jmz","HYPOTHETICAL PROTEIN MJ0781","Methanocaldococcus jannaschii",4,"PRO A 104;HIS A 103;LEU A 155;SER A  61","None","1.20A","1sbrA-2jmzA:undetectable;1sbrB-2jmzA:undetectable","1sbrA-2jmzA:18.40;1sbrB-2jmzA:18.40"],["3VRJ_A_1KXA301_1","HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN;10-MER PEPTIDE","2jmz","HYPOTHETICAL PROTEIN MJ0781","Methanocaldococcus jannaschii",5,"ILE A  52;VAL A  77;TYR A 153;ILE A  59;ILE A  57","None","1.21A","3vrjA-2jmzA:undetectable;3vrjC-2jmzA:undetectable","3vrjA-2jmzA:20.15;3vrjC-2jmzA:12.99"],["5CSW_A_P06A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","2jmz","HYPOTHETICAL PROTEIN MJ0781","Methanocaldococcus jannaschii",3,"PHE A  28;ILE A  15;ASP A  12","None","0.73A","5cswA-2jmzA:undetectable","5cswA-2jmzA:19.23"],["5DQY_A_BEZA401_0","THIOREDOXIN","2jmz","HYPOTHETICAL PROTEIN MJ0781","Methanocaldococcus jannaschii",4,"ILE A  50;PHE A  32;VAL A  77;GLU A  55","None","1.08A","5dqyA-2jmzA:undetectable","5dqyA-2jmzA:17.74"]]