SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jnk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 2jnk HYALURONONGLUCOSAMIN
IDASE
(Clostridium
perfringens) 		3 / 3 GLY A  13
GLU A  40
ASN A  11
 None
 0.73A 1zq9A-2jnkA:
undetectable		 1zq9A-2jnkA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2jnk HYALURONONGLUCOSAMIN
IDASE
(Clostridium
perfringens) 		5 / 12 ASN A 101
ILE A 118
LEU A 110
ASP A 111
GLY A 116
 None
 1.26A 2ycjA-2jnkA:
undetectable		 2ycjA-2jnkA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2jnk HYALURONONGLUCOSAMIN
IDASE
(Clostridium
perfringens) 		3 / 3 ILE A 118
PHE A  84
HIS A  30
 None
 0.67A 3h0aA-2jnkA:
undetectable		 3h0aA-2jnkA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2jnk HYALURONONGLUCOSAMIN
IDASE
(Clostridium
perfringens) 		6 / 12 ILE A  90
ILE A 118
ASN A 101
ASN A 107
LEU A 110
GLY A  86
 None
 1.38A 4r3aB-2jnkA:
undetectable		 4r3aB-2jnkA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 2jnk HYALURONONGLUCOSAMIN
IDASE
(Clostridium
perfringens) 		4 / 7 SER A  64
GLY A  36
ALA A  68
ILE A  41
 None
 0.74A 4yjiA-2jnkA:
undetectable		 4yjiA-2jnkA:
13.54