SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		3 / 3 GLN A   6
TYR A 127
ARG A 128
 None
 0.84A 1gtbA-2jnuA:
undetectable		 1gtbA-2jnuA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 7 ILE A 109
LEU A 112
THR A  29
LEU A  32
 None
 0.91A 1v55A-2jnuA:
1.3
1v55J-2jnuA:
undetectable		 1v55A-2jnuA:
16.82
1v55J-2jnuA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 7 TYR A  69
TRP A  88
GLN A  76
ILE A  83
 None
 1.31A 2ph9A-2jnuA:
undetectable
2ph9B-2jnuA:
undetectable		 2ph9A-2jnuA:
20.69
2ph9B-2jnuA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 6 ARG A  85
GLN A 108
PHE A  43
LEU A  73
 None
 1.13A 3ablP-2jnuA:
3.0
3ablW-2jnuA:
undetectable		 3ablP-2jnuA:
22.63
3ablW-2jnuA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 7 ILE A 109
LEU A 112
THR A  29
LEU A  32
 None
 0.96A 3ag3A-2jnuA:
undetectable
3ag3J-2jnuA:
undetectable		 3ag3A-2jnuA:
16.82
3ag3J-2jnuA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 7 ILE A 109
LEU A 112
THR A  29
LEU A  32
 None
 0.92A 5b1aA-2jnuA:
undetectable
5b1aJ-2jnuA:
undetectable		 5b1aA-2jnuA:
16.82
5b1aJ-2jnuA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 6 ARG A  85
GLN A 108
PHE A  43
LEU A  73
 None
 1.08A 5b1bC-2jnuA:
3.1
5b1bJ-2jnuA:
undetectable		 5b1bC-2jnuA:
22.63
5b1bJ-2jnuA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 7 ILE A 109
LEU A 112
THR A  29
LEU A  32
 None
 0.93A 5xdxA-2jnuA:
1.8
5xdxJ-2jnuA:
undetectable		 5xdxA-2jnuA:
16.82
5xdxJ-2jnuA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 7 ILE A 109
LEU A 112
THR A  29
LEU A  32
 None
 0.87A 6nmfA-2jnuA:
undetectable
6nmfJ-2jnuA:
undetectable		 6nmfA-2jnuA:
16.82
6nmfJ-2jnuA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 7 ILE A 109
LEU A 112
THR A  29
LEU A  32
 None
 0.91A 6nmpA-2jnuA:
1.3
6nmpJ-2jnuA:
undetectable		 6nmpA-2jnuA:
16.82
6nmpJ-2jnuA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2jnu REGULATOR OF
G-PROTEIN SIGNALING
14
(Homo
sapiens) 		4 / 5 ILE A 109
LEU A 112
THR A  29
LEU A  32
 None
 0.85A 6nmpN-2jnuA:
1.4
6nmpW-2jnuA:
undetectable		 6nmpN-2jnuA:
16.82
6nmpW-2jnuA:
14.94