SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jnw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 2jnw DNA EXCISION REPAIR
PROTEIN ERCC-1
(Homo
sapiens) 		3 / 3 VAL A 112
TRP A 121
VAL A 116
 None
 0.99A 2izqC-2jnwA:
undetectable
2izqD-2jnwA:
undetectable		 2izqC-2jnwA:
7.50
2izqD-2jnwA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 2jnw DNA EXCISION REPAIR
PROTEIN ERCC-1
(Homo
sapiens) 		4 / 6 CYH A 194
THR A 195
CYH A 189
ILE A 153
 None
 1.36A 3w9tB-2jnwA:
undetectable		 3w9tB-2jnwA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 2jnw DNA EXCISION REPAIR
PROTEIN ERCC-1
(Homo
sapiens) 		4 / 5 TRP A 200
LEU A 198
VAL A 171
LEU A 182
 None
 1.07A 5xooB-2jnwA:
undetectable		 5xooB-2jnwA:
20.90