SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jo7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2jo7 GLYCOSYLPHOSPHATIDYL
INOSITOL-ANCHORED
MEROZOITE SURFACE
PROTEIN
(Babesia
divergens) 		5 / 12 GLY A  81
GLY A  77
ILE A 289
ASP A 112
VAL A 108
 None
 1.07A 2oxtA-2jo7A:
undetectable		 2oxtA-2jo7A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 2jo7 GLYCOSYLPHOSPHATIDYL
INOSITOL-ANCHORED
MEROZOITE SURFACE
PROTEIN
(Babesia
divergens) 		4 / 7 TYR A 132
LEU A 106
LEU A 133
PHE A 181
 None
 1.24A 3nk2X-2jo7A:
undetectable		 3nk2X-2jo7A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2jo7 GLYCOSYLPHOSPHATIDYL
INOSITOL-ANCHORED
MEROZOITE SURFACE
PROTEIN
(Babesia
divergens) 		4 / 5 VAL A 235
ILE A 254
PHE A 223
PHE A 216
 None
 0.97A 3owxB-2jo7A:
undetectable		 3owxB-2jo7A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2jo7 GLYCOSYLPHOSPHATIDYL
INOSITOL-ANCHORED
MEROZOITE SURFACE
PROTEIN
(Babesia
divergens) 		5 / 12 LEU A 177
ILE A 157
ILE A  99
LEU A 102
VAL A 129
 None
 1.22A 3w68C-2jo7A:
undetectable		 3w68C-2jo7A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2jo7 GLYCOSYLPHOSPHATIDYL
INOSITOL-ANCHORED
MEROZOITE SURFACE
PROTEIN
(Babesia
divergens) 		3 / 3 ARG A  83
ARG A 278
ASP A 283
 None
 1.01A 3wipG-2jo7A:
undetectable
3wipH-2jo7A:
undetectable		 3wipG-2jo7A:
21.45
3wipH-2jo7A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 2jo7 GLYCOSYLPHOSPHATIDYL
INOSITOL-ANCHORED
MEROZOITE SURFACE
PROTEIN
(Babesia
divergens) 		3 / 3 GLY A  95
PRO A  96
GLN A 101
 None
 0.53A 4oltB-2jo7A:
undetectable		 4oltB-2jo7A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 2jo7 GLYCOSYLPHOSPHATIDYL
INOSITOL-ANCHORED
MEROZOITE SURFACE
PROTEIN
(Babesia
divergens) 		3 / 3 GLY A  95
PRO A  96
GLN A 101
 None
 0.60A 4qwpB-2jo7A:
undetectable		 4qwpB-2jo7A:
22.35