SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jpd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_A_SAMA300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	2jpd	DNA EXCISION REPAIR PROTEIN ERCC-1 (Homo sapiens)	5 / 12	LEU A 209 TYR A 212 GLY A 133 LEU A 139 ALA A 165	None	1.14A	3ou6A-2jpdA: undetectable	3ou6A-2jpdA: 21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_B_SAMB300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	2jpd	DNA EXCISION REPAIR PROTEIN ERCC-1 (Homo sapiens)	5 / 12	LEU A 209 TYR A 212 GLY A 133 LEU A 139 ALA A 165	None	1.08A	3ou6B-2jpdA: undetectable	3ou6B-2jpdA: 21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_B_W9TB513_1 (HEMOLYTIC LECTIN CEL-III)	2jpd	DNA EXCISION REPAIR PROTEIN ERCC-1 (Homo sapiens)	4 / 6	CYH A 194 THR A 195 CYH A 189 ILE A 153	None	1.49A	3w9tB-2jpdA: undetectable	3w9tB-2jpdA: 15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKR_A_ID8A601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2jpd	DNA EXCISION REPAIR PROTEIN ERCC-1 (Homo sapiens)	5 / 12	VAL A 171 LEU A 141 SER A 142 ALA A 181 LEU A 182	None	1.00A	5ikrA-2jpdA: undetectable	5ikrA-2jpdA: 13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JVZ_B_FLPB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2jpd	DNA EXCISION REPAIR PROTEIN ERCC-1 (Homo sapiens)	5 / 12	VAL A 171 LEU A 141 SER A 142 ALA A 181 LEU A 182	None	1.09A	5jvzB-2jpdA: undetectable	5jvzB-2jpdA: 13.04

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OU6_A_SAMA300_0","SAM-DEPENDENT METHYLTRANSFERASE","2jpd","DNA EXCISION REPAIR PROTEIN ERCC-1","Homo sapiens",5,"LEU A 209;TYR A 212;GLY A 133;LEU A 139;ALA A 165","None","1.14A","3ou6A-2jpdA:undetectable","3ou6A-2jpdA:21.76"],["3OU6_B_SAMB300_0","SAM-DEPENDENT METHYLTRANSFERASE","2jpd","DNA EXCISION REPAIR PROTEIN ERCC-1","Homo sapiens",5,"LEU A 209;TYR A 212;GLY A 133;LEU A 139;ALA A 165","None","1.08A","3ou6B-2jpdA:undetectable","3ou6B-2jpdA:21.76"],["3W9T_B_W9TB513_1","HEMOLYTIC LECTIN CEL-III","2jpd","DNA EXCISION REPAIR PROTEIN ERCC-1","Homo sapiens",4,"CYH A 194;THR A 195;CYH A 189;ILE A 153","None","1.49A","3w9tB-2jpdA:undetectable","3w9tB-2jpdA:15.12"],["5IKR_A_ID8A601_1","PROSTAGLANDIN G\/H SYNTHASE 2","2jpd","DNA EXCISION REPAIR PROTEIN ERCC-1","Homo sapiens",5,"VAL A 171;LEU A 141;SER A 142;ALA A 181;LEU A 182","None","1.00A","5ikrA-2jpdA:undetectable","5ikrA-2jpdA:13.57"],["5JVZ_B_FLPB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","2jpd","DNA EXCISION REPAIR PROTEIN ERCC-1","Homo sapiens",5,"VAL A 171;LEU A 141;SER A 142;ALA A 181;LEU A 182","None","1.09A","5jvzB-2jpdA:undetectable","5jvzB-2jpdA:13.04"]]