SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jpf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YC2_B_NCAB508_0 (NAD-DEPENDENT DEACETYLASE 2)	2jpf	HYPOTHETICAL PROTEIN (Bordetella parapertussis)	4 / 5	GLN A 56 LEU A 55 GLN A 90 TYR A 63	None	1.45A	1yc2B-2jpfA: undetectable 1yc2C-2jpfA: undetectable	1yc2B-2jpfA: 20.66 1yc2C-2jpfA: 20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A3U_A_NCAA1359_0 (NADH:FLAVIN OXIDOREDUCTASE/NADH OXIDASE)	2jpf	HYPOTHETICAL PROTEIN (Bordetella parapertussis)	4 / 7	THR A 59 TRP A 89 TRP A 36 TYR A 63	None	1.14A	4a3uA-2jpfA: undetectable	4a3uA-2jpfA: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A3U_B_NCAB1359_0 (NADH:FLAVIN OXIDOREDUCTASE/NADH OXIDASE)	2jpf	HYPOTHETICAL PROTEIN (Bordetella parapertussis)	4 / 7	THR A 59 TRP A 89 TRP A 36 TYR A 63	None	1.15A	4a3uB-2jpfA: undetectable	4a3uB-2jpfA: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0T_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	2jpf	HYPOTHETICAL PROTEIN (Bordetella parapertussis)	4 / 5	TYR A 63 SER A 58 GLN A 88 THR A 93	None	1.12A	5n0tA-2jpfA: undetectable	5n0tA-2jpfA: 16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0T_B_SAMB501_1 (PEPTIDE N-METHYLTRANSFERASE)	2jpf	HYPOTHETICAL PROTEIN (Bordetella parapertussis)	4 / 4	TYR A 63 SER A 58 GLN A 88 THR A 93	None	1.17A	5n0tB-2jpfA: undetectable	5n0tB-2jpfA: 16.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YC2_B_NCAB508_0","NAD-DEPENDENT DEACETYLASE 2","2jpf","HYPOTHETICAL PROTEIN","Bordetella parapertussis",4,"GLN A  56;LEU A  55;GLN A  90;TYR A  63","None","1.45A","1yc2B-2jpfA:undetectable;1yc2C-2jpfA:undetectable","1yc2B-2jpfA:20.66;1yc2C-2jpfA:20.66"],["4A3U_A_NCAA1359_0","NADH:FLAVIN OXIDOREDUCTASE\/NADH OXIDASE","2jpf","HYPOTHETICAL PROTEIN","Bordetella parapertussis",4,"THR A  59;TRP A  89;TRP A  36;TYR A  63","None","1.14A","4a3uA-2jpfA:undetectable","4a3uA-2jpfA:18.48"],["4A3U_B_NCAB1359_0","NADH:FLAVIN OXIDOREDUCTASE\/NADH OXIDASE","2jpf","HYPOTHETICAL PROTEIN","Bordetella parapertussis",4,"THR A  59;TRP A  89;TRP A  36;TYR A  63","None","1.15A","4a3uB-2jpfA:undetectable","4a3uB-2jpfA:18.48"],["5N0T_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","2jpf","HYPOTHETICAL PROTEIN","Bordetella parapertussis",4,"TYR A  63;SER A  58;GLN A  88;THR A  93","None","1.12A","5n0tA-2jpfA:undetectable","5n0tA-2jpfA:16.21"],["5N0T_B_SAMB501_1","PEPTIDE N-METHYLTRANSFERASE","2jpf","HYPOTHETICAL PROTEIN","Bordetella parapertussis",4,"TYR A  63;SER A  58;GLN A  88;THR A  93","None","1.17A","5n0tB-2jpfA:undetectable","5n0tB-2jpfA:16.21"]]