SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jpo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)
2jpo PHEROMONE-BINDING
PROTEIN

(Antheraea
polyphemus)
3 / 3 ASN A   7
LEU A   8
HIS A  80
None
0.83A 2q6fB-2jpoA:
undetectable
2q6fB-2jpoA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)
2jpo PHEROMONE-BINDING
PROTEIN

(Antheraea
polyphemus)
5 / 12 GLY A  13
ASP A  17
ALA A  51
LEU A  33
VAL A  29
None
0.95A 2yqzB-2jpoA:
undetectable
2yqzB-2jpoA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
2jpo PHEROMONE-BINDING
PROTEIN

(Antheraea
polyphemus)
3 / 3 GLY A  49
THR A 111
ASN A  53
None
0.67A 3v4tD-2jpoA:
undetectable
3v4tD-2jpoA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
2jpo PHEROMONE-BINDING
PROTEIN

(Antheraea
polyphemus)
3 / 3 ASP A  32
LEU A  33
PHE A  36
None
0.53A 4pthA-2jpoA:
undetectable
4pthA-2jpoA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)
2jpo PHEROMONE-BINDING
PROTEIN

(Antheraea
polyphemus)
3 / 3 ASP A 132
VAL A  62
LEU A 139
None
0.65A 5e5jB-2jpoA:
undetectable
5e5jB-2jpoA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)
2jpo PHEROMONE-BINDING
PROTEIN

(Antheraea
polyphemus)
4 / 4 ASP A  75
GLY A  66
ASP A  63
ASP A 132
None
1.16A 5e72A-2jpoA:
undetectable
5e72A-2jpoA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)
2jpo PHEROMONE-BINDING
PROTEIN

(Antheraea
polyphemus)
3 / 3 LYS A  58
LEU A   8
ILE A 135
None
0.65A 5kc4A-2jpoA:
undetectable
5kc4A-2jpoA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)
2jpo PHEROMONE-BINDING
PROTEIN

(Antheraea
polyphemus)
5 / 11 ILE A  93
ALA A  73
LEU A 133
GLY A 136
ALA A 115
None
1.20A 6ieyA-2jpoA:
undetectable
6ieyB-2jpoA:
undetectable
6ieyA-2jpoA:
19.03
6ieyB-2jpoA:
19.03