SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 2jqj DNA DAMAGE RESPONSE
PROTEIN KINASE DUN1
(Saccharomyces
cerevisiae) 		5 / 9 ALA A  78
ILE A  67
GLY A  59
HIS A  77
ILE A  73
 None
 1.12A 4eatB-2jqjA:
undetectable		 4eatB-2jqjA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 2jqj DNA DAMAGE RESPONSE
PROTEIN KINASE DUN1
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 125
ASN A  96
TYR A 117
ILE A 107
 None
 1.04A 4jtpA-2jqjA:
undetectable		 4jtpA-2jqjA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 2jqj DNA DAMAGE RESPONSE
PROTEIN KINASE DUN1
(Saccharomyces
cerevisiae) 		5 / 12 SER A 101
ASN A 108
LEU A 119
PHE A  80
PHE A 133
 None
 1.37A 6dwnA-2jqjA:
undetectable		 6dwnA-2jqjA:
22.54