SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 2jqq CONSERVED OLIGOMERIC
GOLGI COMPLEX
SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 125
ASP A 128
THR A 132
ILE A 186
GLU A 185
 None
 1.20A 2yzqA-2jqqA:
undetectable		 2yzqA-2jqqA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 2jqq CONSERVED OLIGOMERIC
GOLGI COMPLEX
SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 138
SER A 170
GLU A 229
ASP A 225
 None
 1.12A 3bc9A-2jqqA:
undetectable		 3bc9A-2jqqA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2jqq CONSERVED OLIGOMERIC
GOLGI COMPLEX
SUBUNIT 2
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 113
LEU A 114
PHE A 117
 None
 0.74A 4pthA-2jqqA:
undetectable		 4pthA-2jqqA:
22.79