SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 2jqz E3 UBIQUITIN-PROTEIN
LIGASE SMURF2
(Homo
sapiens) 		5 / 9 LEU A 117
ILE A  77
THR A  50
VAL A  18
ALA A  21
 None
 1.18A 2m9qA-2jqzA:
undetectable		 2m9qA-2jqzA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2jqz E3 UBIQUITIN-PROTEIN
LIGASE SMURF2
(Homo
sapiens) 		4 / 8 VAL A  39
VAL A 134
LEU A 136
VAL A  18
 None
 0.77A 2zujA-2jqzA:
undetectable		 2zujA-2jqzA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 2jqz E3 UBIQUITIN-PROTEIN
LIGASE SMURF2
(Homo
sapiens) 		5 / 10 VAL A  18
LEU A 120
ALA A  37
PRO A  59
LEU A  24
 None
 1.11A 5mm4B-2jqzA:
undetectable		 5mm4B-2jqzA:
21.01