SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jr0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK5_A_T44A1008_1 (SERUM ALBUMIN)	2jr0	N UTILIZATION SUBSTANCE PROTEIN B HOMOLOG (Aquifex aeolicus)	5 / 10	ASP A 9 ALA A 11 LYS A 36 VAL A 33 VAL A 14	None	1.32A	1hk5A-2jr0A: undetectable	1hk5A-2jr0A: 15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JLB_A_NVPA999_1 (HIV-1 RT A-CHAIN)	2jr0	N UTILIZATION SUBSTANCE PROTEIN B HOMOLOG (Aquifex aeolicus)	4 / 8	LEU A 110 VAL A 123 GLY A 120 LEU A 87	None	0.94A	1jlbA-2jr0A: undetectable	1jlbA-2jr0A: 14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MMD_B_29EB603_1 (TRANSPORTER)	2jr0	N UTILIZATION SUBSTANCE PROTEIN B HOMOLOG (Aquifex aeolicus)	5 / 12	ALA A 133 TYR A 131 TYR A 134 SER A 138 SER A 137	None	1.14A	4mmdB-2jr0A: undetectable	4mmdB-2jr0A: 18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	2jr0	N UTILIZATION SUBSTANCE PROTEIN B HOMOLOG (Aquifex aeolicus)	5 / 12	SER A 73 PHE A 122 ASP A 75 GLY A 78 ILE A 65	None	1.34A	6dwnA-2jr0A: undetectable	6dwnA-2jr0A: 16.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HK5_A_T44A1008_1","SERUM ALBUMIN","2jr0","N UTILIZATION SUBSTANCE PROTEIN B HOMOLOG","Aquifex aeolicus",5,"ASP A   9;ALA A  11;LYS A  36;VAL A  33;VAL A  14","None","1.32A","1hk5A-2jr0A:undetectable","1hk5A-2jr0A:15.52"],["1JLB_A_NVPA999_1","HIV-1 RT A-CHAIN","2jr0","N UTILIZATION SUBSTANCE PROTEIN B HOMOLOG","Aquifex aeolicus",4,"LEU A 110;VAL A 123;GLY A 120;LEU A  87","None","0.94A","1jlbA-2jr0A:undetectable","1jlbA-2jr0A:14.11"],["4MMD_B_29EB603_1","TRANSPORTER","2jr0","N UTILIZATION SUBSTANCE PROTEIN B HOMOLOG","Aquifex aeolicus",5,"ALA A 133;TYR A 131;TYR A 134;SER A 138;SER A 137","None","1.14A","4mmdB-2jr0A:undetectable","4mmdB-2jr0A:18.41"],["6DWN_A_AQ4A602_0","CYTOCHROME P450 1A1","2jr0","N UTILIZATION SUBSTANCE PROTEIN B HOMOLOG","Aquifex aeolicus",5,"SER A  73;PHE A 122;ASP A  75;GLY A  78;ILE A  65","None","1.34A","6dwnA-2jr0A:undetectable","6dwnA-2jr0A:16.56"]]