SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jr5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CO4_A_GCSA401_1 (CHITINASE)	2jr5	UPF0350 PROTEIN VC_2471 (Vibrio cholerae)	3 / 3	GLU A 88 HIS A 90 HIS A 91	None	0.93A	3co4A-2jr5A: undetectable	3co4A-2jr5A: 18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CR5_X_PNTX95_0 (PROTEIN S100-B)	2jr5	UPF0350 PROTEIN VC_2471 (Vibrio cholerae)	3 / 3	CYH A 32 PHE A 33 PHE A 29	None	0.99A	3cr5X-2jr5A: undetectable	3cr5X-2jr5A: 26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	2jr5	UPF0350 PROTEIN VC_2471 (Vibrio cholerae)	4 / 4	ILE A 10 GLN A 6 VAL A 45 PHE A 29	None	1.18A	3ieoA-2jr5A: undetectable	3ieoA-2jr5A: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PSS_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2jr5	UPF0350 PROTEIN VC_2471 (Vibrio cholerae)	6 / 12	ILE A 10 ALA A 13 LEU A 47 ALA A 46 PHE A 44 ILE A 77	None	1.35A	4pssA-2jr5A: undetectable	4pssA-2jr5A: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PSY_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2jr5	UPF0350 PROTEIN VC_2471 (Vibrio cholerae)	6 / 12	ILE A 10 ALA A 13 LEU A 47 ALA A 46 PHE A 44 ILE A 77	None	1.31A	4psyA-2jr5A: undetectable	4psyA-2jr5A: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z6F_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2jr5	UPF0350 PROTEIN VC_2471 (Vibrio cholerae)	5 / 12	ILE A 10 ALA A 13 LEU A 47 PHE A 44 ILE A 77	None	1.21A	5z6fA-2jr5A: undetectable	5z6fA-2jr5A: 21.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CO4_A_GCSA401_1","CHITINASE","2jr5","UPF0350 PROTEIN VC_2471","Vibrio cholerae",3,"GLU A  88;HIS A  90;HIS A  91","None","0.93A","3co4A-2jr5A:undetectable","3co4A-2jr5A:18.10"],["3CR5_X_PNTX95_0","PROTEIN S100-B","2jr5","UPF0350 PROTEIN VC_2471","Vibrio cholerae",3,"CYH A  32;PHE A  33;PHE A  29","None","0.99A","3cr5X-2jr5A:undetectable","3cr5X-2jr5A:26.42"],["3IEO_A_AMJA300_0","CARBONIC ANHYDRASE 2","2jr5","UPF0350 PROTEIN VC_2471","Vibrio cholerae",4,"ILE A  10;GLN A   6;VAL A  45;PHE A  29","None","1.18A","3ieoA-2jr5A:undetectable","3ieoA-2jr5A:14.77"],["4PSS_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","2jr5","UPF0350 PROTEIN VC_2471","Vibrio cholerae",6,"ILE A  10;ALA A  13;LEU A  47;ALA A  46;PHE A  44;ILE A  77","None","1.35A","4pssA-2jr5A:undetectable","4pssA-2jr5A:22.37"],["4PSY_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","2jr5","UPF0350 PROTEIN VC_2471","Vibrio cholerae",6,"ILE A  10;ALA A  13;LEU A  47;ALA A  46;PHE A  44;ILE A  77","None","1.31A","4psyA-2jr5A:undetectable","4psyA-2jr5A:22.37"],["5Z6F_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","2jr5","UPF0350 PROTEIN VC_2471","Vibrio cholerae",5,"ILE A  10;ALA A  13;LEU A  47;PHE A  44;ILE A  77","None","1.21A","5z6fA-2jr5A:undetectable","5z6fA-2jr5A:21.57"]]