SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jrb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 2jrb ORF 1 PROTEIN
(Mus
musculus) 		5 / 12 ILE A 352
ALA A 348
LEU A 343
LEU A 307
ILE A 324
 None
 1.03A 1xzxX-2jrbA:
undetectable		 1xzxX-2jrbA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 2jrb ORF 1 PROTEIN
(Mus
musculus) 		5 / 12 ILE A 352
ALA A 348
LEU A 343
LEU A 307
ILE A 324
 None
 1.05A 2h77A-2jrbA:
undetectable		 2h77A-2jrbA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 2jrb ORF 1 PROTEIN
(Mus
musculus) 		5 / 12 ILE A 352
ALA A 348
LEU A 343
LEU A 307
ILE A 324
 None
 1.01A 2h79A-2jrbA:
undetectable		 2h79A-2jrbA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2jrb ORF 1 PROTEIN
(Mus
musculus) 		5 / 12 ALA A 299
VAL A 303
ILE A 324
PHE A 339
LYS A 338
 None
 1.19A 2v95A-2jrbA:
undetectable		 2v95A-2jrbA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 2jrb ORF 1 PROTEIN
(Mus
musculus) 		5 / 12 ILE A 352
ALA A 348
LEU A 343
LEU A 307
ILE A 324
 None
 0.99A 3gwsX-2jrbA:
undetectable		 3gwsX-2jrbA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2jrb ORF 1 PROTEIN
(Mus
musculus) 		5 / 12 ILE A 352
ALA A 348
LEU A 343
LEU A 307
ILE A 324
 None
 1.02A 4lnwA-2jrbA:
undetectable		 4lnwA-2jrbA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2jrb ORF 1 PROTEIN
(Mus
musculus) 		5 / 12 ILE A 352
ALA A 348
LEU A 343
LEU A 307
ILE A 324
 None
 1.03A 4lnxA-2jrbA:
undetectable		 4lnxA-2jrbA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 2jrb ORF 1 PROTEIN
(Mus
musculus) 		3 / 3 THR A 293
ALA A 320
LYS A 321
 None
 0.69A 6fgcA-2jrbA:
undetectable		 6fgcA-2jrbA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 2jrb ORF 1 PROTEIN
(Mus
musculus) 		3 / 3 THR A 293
ALA A 320
LYS A 321
 None
 0.71A 6fgdA-2jrbA:
undetectable		 6fgdA-2jrbA:
11.65